Salmonella Typhimurium and inflammation: a pathogen-centric affair

JE Galán - Nature Reviews Microbiology, 2021 - nature.com
Microbial infections are controlled by host inflammatory responses that are initiated by
innate immune receptors after recognition of conserved microbial products. As inflammation …

L-arginine metabolism as pivotal interface of mutual host–microbe interactions in the gut

B Nüse, T Holland, M Rauh, RG Gerlach, J Mattner - Gut Microbes, 2023 - Taylor & Francis
ABSTRACT L-arginine (L-arg) is a versatile amino acid and a central intestinal metabolite in
mammalian and microbial organisms. Thus, L-arg participates as precursor of multiple …

Salmonella effector SopF regulates PANoptosis of intestinal epithelial cells to aggravate systemic infection

H Yuan, L Zhou, Y Chen, J You, H Hu, Y Li… - Gut …, 2023 - Taylor & Francis
SopF, a newly discovered effector secreted by Salmonella pathogenicity island-1 type III
secretion system (T3SS1), was reported to target phosphoinositide on host cell membrane …

Speaking the host language: how Salmonella effector proteins manipulate the host

TD Pillay, SU Hettiarachchi, J Gan… - …, 2023 - microbiologyresearch.org
Salmonella injects over 40 virulence factors, termed effectors, into host cells to subvert
diverse host cellular processes. Of these 40 Salmonella effectors, at least 25 have been …

[HTML][HTML] Salmonella secretion systems: Differential roles in pathogen-host interactions

H Bao, S Wang, JH Zhao, SL Liu - Microbiological Research, 2020 - Elsevier
The bacterial genus Salmonella includes a large group of food-borne pathogens that cause
a variety of gastrointestinal or systemic diseases in hosts. Salmonella use several secretion …

Host Cell Death Responses to Non-typhoidal Salmonella Infection

MA Wemyss, JS Pearson - Frontiers in immunology, 2019 - frontiersin.org
Salmonella enterica subsp. enterica serovar Typhimurium (S. Typhimurium) is a Gram-
negative bacterium with a broad host range that causes non-typhoidal salmonellosis in …

TRAIL in oncology: From recombinant TRAIL to nano-and self-targeted TRAIL-based therapies

H Dianat-Moghadam, M Heidarifard, A Mahari… - Pharmacological …, 2020 - Elsevier
TNF-related apoptosis-inducing ligand (TRAIL) selectively induces the apoptosis pathway in
tumor cells leading to tumor cell death. Because TRAIL induction can kill tumor cells, cancer …

Modulation of extrinsic apoptotic pathway by intracellular glycosylation

K Seyrek, NV Ivanisenko, C König, IN Lavrik - Trends in Cell Biology, 2024 - cell.com
The importance of post-translational modifications (PTMs), particularly O-GlcNAcylation, of
cytoplasmic proteins in apoptosis has been neglected for quite a while. Modification of …

[HTML][HTML] Salmonella Bloodstream Infections

MJ Worley - Tropical Medicine and Infectious Disease, 2023 - mdpi.com
Salmonella is a major foodborne pathogen of both animals and humans. This bacterium is
responsible for considerable morbidity and mortality world-wide. Different serovars of this …

Reprogramming of cell death pathways by bacterial effectors as a widespread virulence strategy

JJ Wanford, A Hachani, C Odendall - Infection and Immunity, 2022 - journals.asm.org
The modulation of programmed cell death (PCD) processes during bacterial infections is an
evolving arms race between pathogens and their hosts. The initiation of apoptosis …