Biomechanics and mechanobiology of trabecular bone: a review
R Oftadeh, M Perez-Viloria… - Journal of …, 2015 - asmedigitalcollection.asme.org
Trabecular bone is a highly porous, heterogeneous, and anisotropic material which can be
found at the epiphyses of long bones and in the vertebral bodies. Studying the mechanical …
found at the epiphyses of long bones and in the vertebral bodies. Studying the mechanical …
Mechanosensation and transduction in osteocytes
The human skeleton is a miracle of engineering, combining both toughness and light weight.
It does so because bones possess cellular mechanisms wherein external mechanical loads …
It does so because bones possess cellular mechanisms wherein external mechanical loads …
Aging, osteocytes, and mechanotransduction
Abstract Purpose of Review The bone is able to adapt its structure to mechanical signals via
the bone remodeling process governed by mechanosensitive osteocytes. With aging, an …
the bone remodeling process governed by mechanosensitive osteocytes. With aging, an …
The intricate anatomy of the periodontal ligament and its development: Lessons for periodontal regeneration
The periodontal ligament (PDL) connects the tooth root and alveolar bone. It is an aligned
fibrous network that is interposed between, and anchored to, both mineralized surfaces …
fibrous network that is interposed between, and anchored to, both mineralized surfaces …
[PDF][PDF] Mechanical loading and how it affects bone cells: the role of the osteocyte cytoskeleton in maintaining our skeleton
Lack of physical activity causes bone loss and fractures not only in elderly people, but also
in bedridden patients or otherwise inactive youth. This is fast becoming one of the most …
in bedridden patients or otherwise inactive youth. This is fast becoming one of the most …
Osteocyte: the unrecognized side of bone tissue
GY Rochefort, S Pallu, CL Benhamou - Osteoporosis international, 2010 - Springer
Introduction Osteocytes represent 95% of all bone cells. These cells are old osteoblasts that
occupy the lacunar space and are surrounded by the bone matrix. They possess …
occupy the lacunar space and are surrounded by the bone matrix. They possess …
Mechanically induced Ca2+ oscillations in osteocytes release extracellular vesicles and enhance bone formation
The vast osteocytic network is believed to orchestrate bone metabolic activity in response to
mechanical stimuli through production of sclerostin, RANKL, and osteoprotegerin (OPG) …
mechanical stimuli through production of sclerostin, RANKL, and osteoprotegerin (OPG) …
Bone cell mechanosensitivity, estrogen deficiency, and osteoporosis
Adaptation of bone to mechanical stresses normally produces a bone architecture that
combines a proper resistance against failure with a minimal use of material. This adaptive …
combines a proper resistance against failure with a minimal use of material. This adaptive …
TGF-β drives epithelial-mesenchymal transition through δEF1-mediated downregulation of ESRP
Epithelial-mesenchymal transition (EMT) is a crucial event in wound healing, tissue repair
and cancer progression in adult tissues. We have recently shown that transforming growth …
and cancer progression in adult tissues. We have recently shown that transforming growth …
Advances in assessment of bone porosity, permeability and interstitial fluid flow
This contribution reviews recent research performed to assess the porosity and permeability
of bone tissue with the objective of understanding interstitial fluid movement. Bone tissue …
of bone tissue with the objective of understanding interstitial fluid movement. Bone tissue …