Mitochondrial dysfunction and chronic inflammation in polycystic ovary syndrome

SA Dabravolski, NG Nikiforov, AH Eid… - International journal of …, 2021 - mdpi.com
Polycystic ovarian syndrome (PCOS) is the most common endocrine–metabolic disorder
affecting a vast population worldwide; it is linked with anovulation, mitochondrial …

Hyperbaric oxygen treatment—from mechanisms to cognitive improvement

I Gottfried, N Schottlender, U Ashery - Biomolecules, 2021 - mdpi.com
Hyperbaric oxygen treatment (HBOT)—the medical use of oxygen at environmental pressure
greater than one atmosphere absolute—is a very effective therapy for several approved …

The neuroprotective effects of targeting key factors of neuronal cell death in neurodegenerative diseases: The role of ER stress, oxidative stress, and …

MS Karvandi, F Sheikhzadeh Hesari… - Frontiers in Cellular …, 2023 - frontiersin.org
Neuronal loss is one of the striking causes of various central nervous system (CNS)
disorders, including major neurodegenerative diseases, such as Alzheimer's disease (AD) …

Mitochondria-derived peptide MOTS-c: effects and mechanisms related to stress, metabolism and aging

W Wan, L Zhang, Y Lin, X Rao, X Wang, F Hua… - Journal of Translational …, 2023 - Springer
MOTS-c is a peptide encoded by the short open reading frame of the mitochondrial 12S
rRNA gene. It is significantly expressed in response to stress or exercise and translocated to …

Humanin and its pathophysiological roles in aging: A systematic review

D Coradduzza, A Congiargiu, Z Chen, S Cruciani… - Biology, 2023 - mdpi.com
Simple Summary Humanin is a small mitochondrial-derived peptide still under study, with a
number of potential therapeutic applications for various age-related diseases. It plays an …

Too much death can kill you: inhibiting intrinsic apoptosis to treat disease

K Li, MF van Delft, G Dewson - The EMBO Journal, 2021 - embopress.org
Apoptotic cell death is implicated in both physiological and pathological processes. Since
many types of cancerous cells intrinsically evade apoptotic elimination, induction of …

Therapeutic peptides to treat myocardial ischemia-reperfusion injury

C Fernandez Rico, K Konate, E Josse… - Frontiers in …, 2022 - frontiersin.org
Cardiovascular diseases (CVD) including acute myocardial infarction (AMI) rank first in
worldwide mortality and according to the World Health Organization (WHO), they will stay at …

A review of the bioactive ingredients of berries and their applications in curing diseases

A Bilawal, M Ishfaq, MA Gantumur, A Qayum, R Shi… - Food Bioscience, 2021 - Elsevier
Lethal diseases are the most common causes of death in the world that are mostly
associated with nutritional imbalance and quality of life. However, the consumers' interest in …

The role of mitochondria-derived peptides in cardiovascular diseases and their potential as therapeutic targets

SA Dabravolski, NG Nikiforov, AV Starodubova… - International Journal of …, 2021 - mdpi.com
Mitochondria-derived peptides (MDPs) are small peptides hidden in the mitochondrial DNA,
maintaining mitochondrial function and protecting cells under different stresses. Currently …

Antimicrobial peptides mediate apoptosis by changing mitochondrial membrane permeability

H Wang, C Zhang, M Li, C Liu, J Wang, X Ou… - International Journal of …, 2022 - mdpi.com
Changes in mitochondrial membrane permeability are closely associated with mitochondria-
mediated apoptosis. Antimicrobial peptides (AMPs), which have been found to enter cells to …