Mitochondrial dysfunction and chronic inflammation in polycystic ovary syndrome
Polycystic ovarian syndrome (PCOS) is the most common endocrine–metabolic disorder
affecting a vast population worldwide; it is linked with anovulation, mitochondrial …
affecting a vast population worldwide; it is linked with anovulation, mitochondrial …
Hyperbaric oxygen treatment—from mechanisms to cognitive improvement
I Gottfried, N Schottlender, U Ashery - Biomolecules, 2021 - mdpi.com
Hyperbaric oxygen treatment (HBOT)—the medical use of oxygen at environmental pressure
greater than one atmosphere absolute—is a very effective therapy for several approved …
greater than one atmosphere absolute—is a very effective therapy for several approved …
The neuroprotective effects of targeting key factors of neuronal cell death in neurodegenerative diseases: The role of ER stress, oxidative stress, and …
Neuronal loss is one of the striking causes of various central nervous system (CNS)
disorders, including major neurodegenerative diseases, such as Alzheimer's disease (AD) …
disorders, including major neurodegenerative diseases, such as Alzheimer's disease (AD) …
Mitochondria-derived peptide MOTS-c: effects and mechanisms related to stress, metabolism and aging
W Wan, L Zhang, Y Lin, X Rao, X Wang, F Hua… - Journal of Translational …, 2023 - Springer
MOTS-c is a peptide encoded by the short open reading frame of the mitochondrial 12S
rRNA gene. It is significantly expressed in response to stress or exercise and translocated to …
rRNA gene. It is significantly expressed in response to stress or exercise and translocated to …
Humanin and its pathophysiological roles in aging: A systematic review
D Coradduzza, A Congiargiu, Z Chen, S Cruciani… - Biology, 2023 - mdpi.com
Simple Summary Humanin is a small mitochondrial-derived peptide still under study, with a
number of potential therapeutic applications for various age-related diseases. It plays an …
number of potential therapeutic applications for various age-related diseases. It plays an …
Too much death can kill you: inhibiting intrinsic apoptosis to treat disease
K Li, MF van Delft, G Dewson - The EMBO Journal, 2021 - embopress.org
Apoptotic cell death is implicated in both physiological and pathological processes. Since
many types of cancerous cells intrinsically evade apoptotic elimination, induction of …
many types of cancerous cells intrinsically evade apoptotic elimination, induction of …
Therapeutic peptides to treat myocardial ischemia-reperfusion injury
C Fernandez Rico, K Konate, E Josse… - Frontiers in …, 2022 - frontiersin.org
Cardiovascular diseases (CVD) including acute myocardial infarction (AMI) rank first in
worldwide mortality and according to the World Health Organization (WHO), they will stay at …
worldwide mortality and according to the World Health Organization (WHO), they will stay at …
A review of the bioactive ingredients of berries and their applications in curing diseases
Lethal diseases are the most common causes of death in the world that are mostly
associated with nutritional imbalance and quality of life. However, the consumers' interest in …
associated with nutritional imbalance and quality of life. However, the consumers' interest in …
The role of mitochondria-derived peptides in cardiovascular diseases and their potential as therapeutic targets
SA Dabravolski, NG Nikiforov, AV Starodubova… - International Journal of …, 2021 - mdpi.com
Mitochondria-derived peptides (MDPs) are small peptides hidden in the mitochondrial DNA,
maintaining mitochondrial function and protecting cells under different stresses. Currently …
maintaining mitochondrial function and protecting cells under different stresses. Currently …
Antimicrobial peptides mediate apoptosis by changing mitochondrial membrane permeability
H Wang, C Zhang, M Li, C Liu, J Wang, X Ou… - International Journal of …, 2022 - mdpi.com
Changes in mitochondrial membrane permeability are closely associated with mitochondria-
mediated apoptosis. Antimicrobial peptides (AMPs), which have been found to enter cells to …
mediated apoptosis. Antimicrobial peptides (AMPs), which have been found to enter cells to …