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Neuroimaging standards for research into small vessel disease—advances since 2013
Cerebral small vessel disease (SVD) is common during ageing and can present as stroke,
cognitive decline, neurobehavioural symptoms, or functional impairment. SVD frequently …
cognitive decline, neurobehavioural symptoms, or functional impairment. SVD frequently …
Small vessel disease: mechanisms and clinical implications
JM Wardlaw, C Smith, M Dichgans - The Lancet Neurology, 2019 - thelancet.com
Small vessel disease is a disorder of cerebral microvessels that causes white matter
hyperintensities and several other common abnormalities (eg, recent small subcortical …
hyperintensities and several other common abnormalities (eg, recent small subcortical …
What are white matter hyperintensities made of? Relevance to vascular cognitive impairment
JM Wardlaw, MC Valdés Hernández… - Journal of the …, 2015 - ahajournals.org
White matter hyperintensities (WMH) of presumed vascular origin, also referred to as
leukoaraiosis, are a very common finding on brain magnetic resonance imaging (MRI) or …
leukoaraiosis, are a very common finding on brain magnetic resonance imaging (MRI) or …
[HTML][HTML] Stroke injury, cognitive impairment and vascular dementia
The global burden of ischaemic strokes is almost 4-fold greater than haemorrhagic strokes.
Current evidence suggests that 25–30% of ischaemic stroke survivors develop immediate or …
Current evidence suggests that 25–30% of ischaemic stroke survivors develop immediate or …
Update on cerebral small vessel disease: a dynamic whole-brain disease
Y Shi, JM Wardlaw - Stroke and vascular neurology, 2016 - svn.bmj.com
Cerebral small vessel disease (CSVD) is a very common neurological disease in older
people. It causes stroke and dementia, mood disturbance and gait problems. Since it is …
people. It causes stroke and dementia, mood disturbance and gait problems. Since it is …
The pathology and pathophysiology of vascular dementia
RN Kalaria - Neuropharmacology, 2018 - Elsevier
Vascular dementia (VaD) is widely recognised as the second most common type of
dementia. Consensus and accurate diagnosis of clinically suspected VaD relies on wide …
dementia. Consensus and accurate diagnosis of clinically suspected VaD relies on wide …
The potential impact of neuroimaging and translational research on the clinical management of lacunar stroke
Lacunar infarcts represent one of the most frequent subtypes of ischemic strokes and may
represent the first recognizable manifestation of a progressive disease of the small …
represent the first recognizable manifestation of a progressive disease of the small …
The overlap between vascular disease and Alzheimer's disease-lessons from pathology
J Attems, KA Jellinger - BMC medicine, 2014 - Springer
Recent epidemiological and clinico-pathological data indicate considerable overlap
between cerebrovascular disease (CVD) and Alzheimer's disease (AD) and suggest …
between cerebrovascular disease (CVD) and Alzheimer's disease (AD) and suggest …
A novel imaging marker for small vessel disease based on skeletonization of white matter tracts and diffusion histograms
E Baykara, B Gesierich, R Adam… - Annals of …, 2016 - Wiley Online Library
Objective To establish a fully automated, robust imaging marker for cerebral small vessel
disease (SVD) and related cognitive impairment that is easy to implement, reflects disease …
disease (SVD) and related cognitive impairment that is easy to implement, reflects disease …
Advances in understanding the pathophysiology of lacunar stroke: a review
RW Regenhardt, AS Das, EH Lo, LR Caplan - JAMA neurology, 2018 - jamanetwork.com
Importance Stroke is the second leading cause of death in the world, and nearly one-third of
ischemic strokes are lacunar strokes (LSs) or small subcortical infarcts. Although smaller in …
ischemic strokes are lacunar strokes (LSs) or small subcortical infarcts. Although smaller in …