Chronic inflammatory state in obesity causes dysregulation of the endocrine and paracrine
actions of adipocyte-derived factors, which disrupt vascular homeostasis and contribute to …

Metabolic syndrome is a collection of cardiometabolic risk factors that includes obesity,
insulin resistance, hypertension and dyslipidemia. Although there has been significant …

Obesity is often characterized by increased oxidative stress and exacerbated inflammatory
outcomes accompanying infiltration of immune cells in adipocytes. The oxidative stress …

Parallel to the increasing prevalence of obesity in the world, the mortality from
cardiovascular disease has also increased. Low-grade chronic inflammation in obesity …

Regulated production of reactive oxygen species (ROS)/reactive nitrogen species (RNS)
adequately balanced by antioxidant systems is a prerequisite for the participation of these …

Aging is associated with impaired vascular endothelial function, as indicated in part by
reduced endothelium-dependent dilation (EDD). Decreased EDD with aging is thought to be …

Background—Indirect evidence implicates endothelial dysfunction in the pathogenesis of
vascular diseases associated with obstructive sleep apnea (OSA). We investigated directly …

Key point Optimal vascular function is critical for health, and endurance training (ET) has
previously been shown to be an effective method of improving this. Sprint interval training …

Sleep-disordered breathing and obstructive sleep apnea (OSA) are highly prevalent
disorders throughout the lifespan, which may affect up to 2–10% of the population, and have …

Objective—To evaluate the role of early-life exposure to airborne fine particulate matter
(diameter,< 2.5 μm [PM2. 5]) pollution on metabolic parameters, inflammation, and adiposity; …