Recently, a range of prescription and over-the-counter drugs have been reportedly used as
Novel Psychoactive Substances (NPS), due to their potential for abuse resulting from their …

Background: Transcranial magnetic stimulation can be combined with electromyography
(TMS-EMG) and electroencephalography (TMS-EEG) to evaluate the excitatory and …

Since the discovery that certain flavonoids (namely flavones) specifically recognise the
central BDZ receptors, several efforts have been made to identify naturally occurring GABAA …

BACKGROUND: Cortical inhibition (CI) deficits assessed by transcranial magnetic
stimulation paradigms, short-interval cortical inhibition (SICI), and cortical silent period …

Purpose/Background A recent years' increase in both prescribing and availability of second-
generation antipsychotics (SGAs) has been observed. According to the literature, typically …

Although antipsychotic drugs are mainly used for treating schizophrenia, they are widely
used for treating various psychiatric diseases in adults, the elderly, adolescents and even …

The treatment of bipolar depression is one of the most challenging issues in contemporary
psychiatry. Currently only quetiapine and the olanzapine–fluoxetine combination are …

Dysfunction of the GABA system is considered to play a role in the pathology of
schizophrenia. Individual subunits of GABAA/Benzodiazepine (BZ) receptor complex have …

Aripiprazole is a D2-like receptor (D2R) partial agonist with a favourable clinical profile.
Previous investigations indicated that acute and short-term administration of aripiprazole …

The GABA A receptor is implicated in the pathophysiology of schizophrenia and regulated
by PKA signalling. Current antipsychotics bind with D 2-like receptors, but not the GABA A …