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Current developments of coumarin-based anti-cancer agents in medicinal chemistry
S Emami, S Dadashpour - European Journal of Medicinal Chemistry, 2015 - Elsevier
Cancer is one of the leading health hazards and the prominent cause of death in the world.
A number of anticancer agents are currently in clinical practice and used for treatment of …
A number of anticancer agents are currently in clinical practice and used for treatment of …
Coumarin heterocyclic derivatives: chemical synthesis and biological activity
FG Medina, JG Marrero, M Macías-Alonso… - Natural product …, 2015 - pubs.rsc.org
Coumarin heterocyclic derivatives: chemical synthesis and biological activity - Natural Product
Reports (RSC Publishing) DOI:10.1039/C4NP00162A Royal Society of Chemistry View PDF …
Reports (RSC Publishing) DOI:10.1039/C4NP00162A Royal Society of Chemistry View PDF …
[HTML][HTML] Recent advances in the synthesis of coumarin derivatives from different starting materials
The study of coumarin dates back to 1820 when coumarin was first extracted from tonka
bean by Vogel. Compounds containing coumarin backbone are a very important group of …
bean by Vogel. Compounds containing coumarin backbone are a very important group of …
Multitarget compounds bearing tacrine-and donepezil-like structural and functional motifs for the potential treatment of Alzheimer's disease
L Ismaili, B Refouvelet, M Benchekroun, S Brogi… - Progress in …, 2017 - Elsevier
Alzheimer's disease is a multifactorial and fatal neurodegenerative disorder characterized
by decline of cholinergic function, deregulation of other neurotransmitter systems, β-amyloid …
by decline of cholinergic function, deregulation of other neurotransmitter systems, β-amyloid …
Synthesis and biological properties of coumarin derivatives. A review
Coumarin and its derivatives are widely used as scaffolds in the synthesis of new
heterocyclic systems. This review focuses on current developments in the synthesis of …
heterocyclic systems. This review focuses on current developments in the synthesis of …
Coumarins as cholinesterase inhibitors: A review
LG de Souza, MN Rennó, JD Figueroa-Villar - Chemico-biological …, 2016 - Elsevier
The first report in literature of the isolation of coumarin was in the year 1820. After this report,
other papers were published demonstrating the isolation and synthesis of coumarin and …
other papers were published demonstrating the isolation and synthesis of coumarin and …
[HTML][HTML] Current and novel therapeutic molecules and targets in Alzheimer's disease
Alzheimer's disease (AD) is a neurodegenerative disorder in which the death of brain cells
causes memory loss and cognitive decline, ie, dementia. The disease starts with mild …
causes memory loss and cognitive decline, ie, dementia. The disease starts with mild …
Magnetic nanoparticle-supported eosin Y salt [SB-DABCO@ eosin] as an efficient heterogeneous photocatalyst for the multi-component synthesis of chromeno [4, 3-b] …
Heterogeneous photocatalysts present a favourable procedure to realize green and eco-
friendly organic reactions. We have demonstrated an SB-DABCO@ eosin catalyst in a green …
friendly organic reactions. We have demonstrated an SB-DABCO@ eosin catalyst in a green …
A review on flavonoid-based scaffolds as multi-target-directed ligands (MTDLs) for Alzheimer's disease
Abstract Alzheimer's disease (AD), the most common form of dementia, is a multifactorial
neurodegenerative disease. The target enzymes inhibition including cholinesterase, beta …
neurodegenerative disease. The target enzymes inhibition including cholinesterase, beta …
Piperazine skeleton in the structural modification of natural products: a review
RH Zhang, HY Guo, H Deng, J Li… - Journal of enzyme …, 2021 - Taylor & Francis
Piperazine moiety is a cyclic molecule containing two nitrogen atoms in positions 1 and 4, as
well as four carbon atoms. Piperazine is one of the most sought heterocyclics for the …
well as four carbon atoms. Piperazine is one of the most sought heterocyclics for the …