Antibody response to SARS-CoV-2 infection in humans: A systematic review
N Post, D Eddy, C Huntley, MCI Van Schalkwyk… - PloS one, 2020 - journals.plos.org
Background Progress in characterising the humoral immune response to Severe Acute
Respiratory Syndrome 2 (SARS-CoV-2) has been rapid but areas of uncertainty persist …
Respiratory Syndrome 2 (SARS-CoV-2) has been rapid but areas of uncertainty persist …
Antibody-mediated neutralization of SARS-CoV-2
Neutralizing antibodies can block infection, clear pathogens, and are essential to provide
long-term immunity. Since the onset of the pandemic, SARS-CoV-2 neutralizing antibodies …
long-term immunity. Since the onset of the pandemic, SARS-CoV-2 neutralizing antibodies …
Map** neutralizing and immunodominant sites on the SARS-CoV-2 spike receptor-binding domain by structure-guided high-resolution serology
Analysis of the specificity and kinetics of neutralizing antibodies (nAbs) elicited by SARS-
CoV-2 infection is crucial for understanding immune protection and identifying targets for …
CoV-2 infection is crucial for understanding immune protection and identifying targets for …
[HTML][HTML] Affinity maturation of SARS-CoV-2 neutralizing antibodies confers potency, breadth, and resilience to viral escape mutations
Antibodies elicited by infection accumulate somatic mutations in germinal centers that can
increase affinity for cognate antigens. We analyzed 6 independent groups of clonally related …
increase affinity for cognate antigens. We analyzed 6 independent groups of clonally related …
A dynamic COVID-19 immune signature includes associations with poor prognosis
Improved understanding and management of COVID-19, a potentially life-threatening
disease, could greatly reduce the threat posed by its etiologic agent, SARS-CoV-2. Toward …
disease, could greatly reduce the threat posed by its etiologic agent, SARS-CoV-2. Toward …
Effect of an inactivated vaccine against SARS-CoV-2 on safety and immunogenicity outcomes: interim analysis of 2 randomized clinical trials
S **a, K Duan, Y Zhang, D Zhao, H Zhang, Z **e, X Li… - Jama, 2020 - jamanetwork.com
Importance A vaccine against coronavirus disease 2019 (COVID-19) is urgently needed.
Objective To evaluate the safety and immunogenicity of an investigational inactivated whole …
Objective To evaluate the safety and immunogenicity of an investigational inactivated whole …
Escape from neutralizing antibodies by SARS-CoV-2 spike protein variants
Neutralizing antibodies elicited by prior infection or vaccination are likely to be key for future
protection of individuals and populations against SARS-CoV-2. Moreover, passively …
protection of individuals and populations against SARS-CoV-2. Moreover, passively …
Longitudinal observation and decline of neutralizing antibody responses in the three months following SARS-CoV-2 infection in humans
Antibody responses to SARS-CoV-2 can be detected in most infected individuals 10–15 d
after the onset of COVID-19 symptoms. However, due to the recent emergence of SARS …
after the onset of COVID-19 symptoms. However, due to the recent emergence of SARS …
Vaccine breakthrough infections with SARS-CoV-2 variants
E Hacisuleyman, C Hale, Y Saito… - … England Journal of …, 2021 - Mass Medical Soc
Emerging variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are of
clinical concern. In a cohort of 417 persons who had received the second dose of BNT162b2 …
clinical concern. In a cohort of 417 persons who had received the second dose of BNT162b2 …
[HTML][HTML] Maturation and persistence of the anti-SARS-CoV-2 memory B cell response
Memory B cells play a fundamental role in host defenses against viruses, but to date, their
role has been relatively unsettled in the context of SARS-CoV-2. We report here a …
role has been relatively unsettled in the context of SARS-CoV-2. We report here a …