Exploring huntington's disease diagnosis via artificial intelligence models: a comprehensive review

S Ganesh, T Chithambaram, NR Krishnan, DR Vincent… - Diagnostics, 2023 - mdpi.com
Huntington's Disease (HD) is a devastating neurodegenerative disorder characterized by
progressive motor dysfunction, cognitive impairment, and psychiatric symptoms. The early …

[HTML][HTML] Distinct placental molecular processes associated with early-onset and late-onset preeclampsia

Z Ren, Y Gao, Y Gao, G Liang, Q Chen, S Jiang… - Theranostics, 2021 - ncbi.nlm.nih.gov
Background: Patients with preeclampsia display a spectrum of onset time and severity of
clinical presentation, yet the underlying molecular bases for the early-onset and late-onset …

OncoOmics approaches to reveal essential genes in breast cancer: a panoramic view from pathogenesis to precision medicine

A López-Cortés, C Paz-y-Miño, S Guerrero… - Scientific reports, 2020 - nature.com
Breast cancer (BC) is the leading cause of cancer-related death among women and the
most commonly diagnosed cancer worldwide. Although in recent years large-scale efforts …

Gene prioritization, communality analysis, networking and metabolic integrated pathway to better understand breast cancer pathogenesis

A López-Cortés, C Paz-y-Miño, A Cabrera-Andrade… - Scientific reports, 2018 - nature.com
Consensus strategy was proved to be highly efficient in the recognition of gene-disease
association. Therefore, the main objective of this study was to apply theoretical approaches …

GUILDify v2. 0: A tool to identify molecular networks underlying human diseases, their comorbidities and their druggable targets

J Aguirre-Plans, J Piñero, F Sanz, LI Furlong… - Journal of molecular …, 2019 - Elsevier
The genetic basis of complex diseases involves alterations on multiple genes. Unraveling
the interplay between these genetic factors is key to the discovery of new biomarkers and …

[PDF][PDF] Study of preeclampsia in placenta, kidney, and hepatic diseases

PC Situmorang, S Ilyas - Asian Journal of Pharmaceutical and …, 2018 - researchgate.net
Preeclampsia (PE) have a high risk of pregnancy disorder and can cause liver and kidney
disease. PE is a dangerous disease in Indonesia with a high risk of cardiovascular death …

Hierarchical lncRNA regulatory network in early-onset severe preeclampsia

H Liu, Z Wang, Y Li, Q Chen, S Jiang, Y Gao, J Wang… - BMC biology, 2024 - Springer
Background Recent studies have shown that several long non-coding RNAs (lncRNAs) in
the placenta are associated with preeclampsia (PE). However, the extent to which lncRNAs …

NFBTA: a potent cytotoxic agent against glioblastoma

H Turkez, FR Nóbrega, O Ozdemir, CSM Bezerra Filho… - Molecules, 2019 - mdpi.com
Piplartine (PPL), also known as piperlongumine, is a biologically active alkaloid extracted
from the Piper genus which has been found to have highly effective anticancer activity …

Collagen I induces preeclampsia-like symptoms by suppressing proliferation and invasion of trophoblasts

Y Feng, X Chen, H Wang, X Chen, Z Lan, P Li… - Frontiers in …, 2021 - frontiersin.org
Preeclampsia is a common obstetric disorder affecting 2-8% of pregnancy worldwide.
Fibrosis is an important histological change occurring in preeclamptic placenta, and might …