Activatable nano-photosensitizers for precise photodynamic cancer therapy

Z Li, Z Zhou, Y Wang, J Wang, L Zhou… - Coordination Chemistry …, 2023 - Elsevier
Owing to the excellent cell ablation ability and low side effects, photodynamic therapy (PDT)
plays an important role in disease treatment, especially cancer. However, most PDT agents …

Responsive hydrogel dressings for intelligent wound management

S Wang, WY Wu, JCC Yeo, XYD Soo, W Thitsartarn… - …, 2023 - Wiley Online Library
Due to global aging problems, the rising number of patients suffering from chronic or hard‐to‐
heal acute wounds imposes a significant burden on healthcare systems. Wound healing is a …

Controlling the biodistribution and clearance of nanomedicines

H Cabral, J Li, K Miyata, K Kataoka - Nature Reviews Bioengineering, 2024 - nature.com
Nanomedicines improve drug bioavailability, the dose–response relationship, targeting
ability, efficacy and safety compared to conventional freely administered drugs …

[HTML][HTML] Unleashing the power of porphyrin photosensitizers: Illuminating breakthroughs in photodynamic therapy

A Akbar, S Khan, T Chatterjee, M Ghosh - Journal of Photochemistry and …, 2023 - Elsevier
This comprehensive review provides the current trends and recent developments of
porphyrin-based photosensitizers. We discuss their evolution from first-generation to third …

Biomolecule-mimetic nanomaterials for photothermal and photodynamic therapy of cancers: Bridging nanobiotechnology and biomedicine

P He, G Yang, D Zhu, H Kong… - Journal of …, 2022 - Springer
Nanomaterial-based phototherapy has become an important research direction for cancer
therapy, but it still to face some obstacles, such as the toxic side effects and low target …

Killing three birds with one stone: Multi-stage metabolic regulation mediated by clinically usable berberine liposome to overcome photodynamic immunotherapy …

C Zheng, W Luo, Y Liu, J Chen, H Deng, Z Zhou… - Chemical Engineering …, 2023 - Elsevier
Nowadays, photodynamic therapy (PDT) has become a novel effect modality for cancer
therapy. But, facing the extremely hypoxic tumor microenvironment, the efficacy of PDT is still …

Biocompatible conductive hydrogels: applications in the field of biomedicine

Y Hong, Z Lin, Y Yang, T Jiang, J Shang… - International Journal of …, 2022 - mdpi.com
The impact of COVID-19 has rendered medical technology an important factor to maintain
social stability and economic increase, where biomedicine has experienced rapid …

Multifunctional Silver‐Enzyme Nanogels Assembly with Efficient Trienzyme Cascades for Synergistic Diabetic Wound Healing

Y Ma, X Lai, X Luo, Z Luo, L Mao, H Zhu… - Advanced Functional …, 2024 - Wiley Online Library
Diabetic wound healing presents a persistent clinical challenge, often characterized by
prolonged healing times, and can be particularly difficult to achieve in a hyperglycemic …

[HTML][HTML] Innovative strategies for photodynamic therapy against hypoxic tumor

X Li, L Chen, M Huang, S Zeng, J Zheng, S Peng… - Asian Journal of …, 2023 - Elsevier
Photodynamic therapy (PDT) is applied as a robust therapeutic option for tumor, which
exhibits some advantages of unique selectivity and irreversible damage to tumor cells …

[HTML][HTML] Towards overcoming obstacles of type II photodynamic therapy: Endogenous production of light, photosensitizer, and oxygen

L Yu, Z Liu, W Xu, K **, J Liu, X Zhu, Y Zhang… - … pharmaceutica Sinica B, 2024 - Elsevier
Conventional photodynamic therapy (PDT) approaches face challenges including limited
light penetration, low uptake of photosensitizers by tumors, and lack of oxygen in tumor …