Neural heterogeneity controls computations in spiking neural networks
The brain is composed of complex networks of interacting neurons that express
considerable heterogeneity in their physiology and spiking characteristics. How does this …
considerable heterogeneity in their physiology and spiking characteristics. How does this …
Rethinking the external globus pallidus and information flow in cortico‐basal ganglia‐thalamic circuits
For decades, the external globus pallidus (GPe) has been viewed as a passive way‐station
in the indirect pathway of the cortico‐basal ganglia‐thalamic (CBGT) circuit, sandwiched …
in the indirect pathway of the cortico‐basal ganglia‐thalamic (CBGT) circuit, sandwiched …
Neurophysiological avenues to better conceptualizing adaptive cognition
We delve into the human brain's remarkable capacity for adaptability and sustained
cognitive functioning, phenomena traditionally encompassed as executive functions or …
cognitive functioning, phenomena traditionally encompassed as executive functions or …
PyRates—A code-generation tool for modeling dynamical systems in biology and beyond
The mathematical study of real-world dynamical systems relies on models composed of
differential equations. Numerical methods for solving and analyzing differential equation …
differential equations. Numerical methods for solving and analyzing differential equation …
Mean-field approximations of networks of spiking neurons with short-term synaptic plasticity
Low-dimensional descriptions of spiking neural network dynamics are an effective tool for
bridging different scales of organization of brain structure and function. Recent advances in …
bridging different scales of organization of brain structure and function. Recent advances in …
Dynamical mechanism of parkinsonian beta oscillation in a heterogenous subthalamopallidal network
X Wang, Y Yu, F Han, Q Wang - Nonlinear Dynamics, 2023 - Springer
Dysfunction of basal ganglia is associated with the pathogenesis of Parkinson's disease
including alteration of firing rate and excessive beta-band (13-30 Hz) synchronization …
including alteration of firing rate and excessive beta-band (13-30 Hz) synchronization …
Optogenetic stimulation of primary motor cortex regulates beta oscillations in the basal ganglia: A Computational study
Y Yu, Y Fan, S Hou, Q Wang - Communications in Nonlinear Science and …, 2023 - Elsevier
The primary motor cortex (M1) contains interconnected and diverse layers that play an
important role in motor execution. In recent years, M1 has emerged as one of the hot targets …
important role in motor execution. In recent years, M1 has emerged as one of the hot targets …
Synaptic Changes in Pallidostriatal Circuits Observed in the Parkinsonian Model Triggers Abnormal Beta Synchrony with Accurate Spatio-temporal Properties across …
Excessive oscillatory activity across basal ganglia (BG) nuclei in the β frequencies (12–30
Hz) is a hallmark of Parkinson's disease (PD). While the link between oscillations and …
Hz) is a hallmark of Parkinson's disease (PD). While the link between oscillations and …
Synaptic network structure shapes cortically evoked spatio-temporal responses of STN and GPe neurons in a computational model
Introduction The basal ganglia (BG) are involved in motor control and play an essential role
in movement disorders such as hemiballismus, dystonia, and Parkinson's disease. Neurons …
in movement disorders such as hemiballismus, dystonia, and Parkinson's disease. Neurons …
Effects of neural heterogeneity on spiking neural network dynamics
The brain is composed of complex networks of interacting neurons that express
considerable heterogeneity in their physiology and spiking characteristics. How does neural …
considerable heterogeneity in their physiology and spiking characteristics. How does neural …