Architectural, compositional, and mechanical gradients are present in many interfacial
tissues in the body. Yet desired for regeneration, the recreation of these complex natural …

Extracellular vesicle (EV)-based approaches for promoting angiogenesis have shown
promising results. Yet, further development is needed in vehicles that prolong EV exposure …

Cell volume and shape changes play a pivotal role in cellular mechanotransduction,
governing cellular responses to external loading. Understanding the dynamics of cell …

Articular cartilage plays a crucial role in joint function by providing a smooth, load-bearing
surface that facilitates movement and absorbs mechanical impact. Chondrocytes, the cells …

Knee joint has a complex anatomy and it is the largest joint of the human body. The ends of
the bones within the knee joint are covered with a smooth, nearly frictionless articular …

Due to their high-water content, biocompatibility, and ability to mimic the native tissue's
extracellular matrix, hydrogels are commonly used for acellular cartilage repair applications …