Changing epidemiology of hepatocellular carcinoma in Asia

C Zhang, Y Cheng, S Zhang, J Fan, Q Gao - Liver International, 2022 - Wiley Online Library
Liver cancer is the fifth most common cancer and the second leading cause of malignant
death in Asia, and Asia reports 72.5% of the world's cases in 2020. As the most common …

Hepatitis virus and hepatocellular carcinoma: recent advances

C Shen, X Jiang, M Li, Y Luo - Cancers, 2023 - mdpi.com
Simple Summary Hepatocellular carcinoma (HCC) is a global health challenge. Hepatitis
virus infection (including HBV, HCV and HDV) is one of the major risk factors for HCC …

Obesity and the risk of primary liver cancer: A systematic review and meta-analysis

W Sohn, HW Lee, S Lee, JH Lim… - Clinical and …, 2020 - pmc.ncbi.nlm.nih.gov
Background/Aims In this systematic review and meta-analysis, we aimed to clarify the effect
of obesity on the occurrence of and mortality from primary liver cancer. Methods This study …

Non-alcoholic fatty liver disease and alcohol-related liver disease: two intertwined entities

F Idalsoaga, AV Kulkarni, OY Mousa, M Arrese… - Frontiers in …, 2020 - frontiersin.org
Non-alcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease
worldwide, with a prevalence of 25–30%. Since its first description in 1980, NAFLD has …

Genomic medicine and implications for hepatocellular carcinoma prevention and therapy

R Dhanasekaran, JC Nault, LR Roberts… - Gastroenterology, 2019 - Elsevier
The pathogenesis of hepatocellular carcinoma (HCC) is poorly understood, but recent
advances in genomics have increased our understanding of the mechanisms by which …

[HTML][HTML] Impact of diabetes, obesity, and dyslipidemia on the risk of hepatocellular carcinoma in patients with chronic liver diseases

HS Shin, BG Jun, SW Yi - Clinical and Molecular Hepatology, 2022 - ncbi.nlm.nih.gov
Despite the increasing prevalence of metabolic disorders, the potential effects of metabolic
factors on hepatocellular carcinoma (HCC) development in individuals with chronic liver …

[HTML][HTML] Oxidative stress and redox signaling in the pathophysiology of liver diseases

RGR Mooli, D Mukhi… - Comprehensive …, 2022 - ncbi.nlm.nih.gov
The increased production of derivatives of molecular oxygen and nitrogen in the form of
reactive oxygen species (ROS) and reactive nitrogen species (RNS) lead to molecular …

[HTML][HTML] The effect of moderate alcohol drinking in nonalcoholic fatty liver disease

JH Choi, W Sohn, YK Cho - Clinical and Molecular Hepatology, 2020 - ncbi.nlm.nih.gov
Nonalcoholic fatty liver disease (NAFLD) is defined by fat accumulation in liver that is not
caused by excessive alcohol consumption. Safe limits of alcohol consumption in NAFLD are …

[HTML][HTML] Impact of aging on primary liver cancer: epidemiology, pathogenesis and therapeutics

RIR Macias, MJ Monte, MA Serrano… - Aging (Albany …, 2021 - ncbi.nlm.nih.gov
Aging involves progressive physiological and metabolic reprogramming to adapt to gradual
deterioration of organs and functions. This includes mechanisms of defense against pre …

Hepatitis C in pregnancy: a unique opportunity to improve the hepatitis C cascade of care

T Kushner, NA Terrault - Hepatology communications, 2019 - journals.lww.com
Hepatitis C has increasingly affected women of child‐bearing age over the past few years as
a result of the opioid epidemic. In this review, we discuss the effect of hepatitis C on …