Gut-microbiota-derived metabolites maintain gut and systemic immune homeostasis

J Wang, N Zhu, X Su, Y Gao, R Yang - Cells, 2023 - mdpi.com
The gut microbiota, including bacteria, archaea, fungi, viruses and phages, inhabits the
gastrointestinal tract. This commensal microbiota can contribute to the regulation of host …

The gut microbiome as a modulator of healthy ageing

TS Ghosh, F Shanahan, PW O'Toole - … Reviews Gastroenterology & …, 2022 - nature.com
The gut microbiome is a contributory factor in ageing-related health loss and in several non-
communicable diseases in all age groups. Some age-linked and disease-linked …

[HTML][HTML] Excess body weight: Novel insights into its roles in obesity comorbidities

X Zhang, S Ha, HCH Lau, J Yu - Seminars in cancer biology, 2023 - Elsevier
Excess body weight is a global health problem due to sedentary lifestyle and unhealthy diet,
affecting 2 billion population worldwide. Obesity is a major risk factor for metabolic diseases …

Short chain fatty acids: Microbial metabolites for gut-brain axis signalling

KJ O'Riordan, MK Collins, GM Moloney… - Molecular and Cellular …, 2022 - Elsevier
The role of the intestinal microbiota as a regulator of gut-brain axis signalling has risen to
prominence in recent years. Understanding the relationship between the gut microbiota, the …

Gut microbiota in obesity

BN Liu, XT Liu, ZH Liang… - World journal of …, 2021 - pmc.ncbi.nlm.nih.gov
Obesity is a major global health problem determined by heredity and environment, and its
incidence is increasing yearly. In recent years, increasing evidence linking obesity to the gut …

Role of the gut–brain axis in energy and glucose metabolism

HR Wachsmuth, SN Weninger, FA Duca - Experimental & molecular …, 2022 - nature.com
The gastrointestinal tract plays a role in the development and treatment of metabolic
diseases. During a meal, the gut provides crucial information to the brain regarding …

Gut microbiota in overweight and obesity: crosstalk with adipose tissue

PD Cani, M Van Hul - Nature Reviews Gastroenterology & Hepatology, 2024 - nature.com
Overweight and obesity are characterized by excessive fat mass accumulation produced
when energy intake exceeds energy expenditure. One plausible way to control energy …

Functions of gut microbiota metabolites, current status and future perspectives

J Liu, Y Tan, H Cheng, D Zhang, W Feng… - Aging and …, 2022 - pmc.ncbi.nlm.nih.gov
Gut microbiota, a collection of microorganisms that live within gastrointestinal tract, provides
crucial signaling metabolites for the physiological of hosts. In healthy state, gut microbiota …

Supplementation with Akkermansia muciniphila in overweight and obese human volunteers: a proof-of-concept exploratory study

C Depommier, A Everard, C Druart, H Plovier… - Nature medicine, 2019 - nature.com
Metabolic syndrome is characterized by a constellation of comorbidities that predispose
individuals to an increased risk of develo** cardiovascular pathologies as well as type 2 …

[HTML][HTML] Ketogenic diets alter the gut microbiome resulting in decreased intestinal Th17 cells

QY Ang, M Alexander, JC Newman, Y Tian, J Cai… - Cell, 2020 - cell.com
Very low-carbohydrate, high-fat ketogenic diets (KDs) induce a pronounced shift in
metabolic fuel utilization that elevates circulating ketone bodies; however, the …