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Drug resistance in influenza A virus: the epidemiology and management
Influenza A virus (IAV) is the sole cause of the unpredictable influenza pandemics and
deadly zoonotic outbreaks and constitutes at least half of the cause of regular annual …
deadly zoonotic outbreaks and constitutes at least half of the cause of regular annual …
Zoonotic potential of influenza A viruses: a comprehensive overview
Influenza A viruses (IAVs) possess a great zoonotic potential as they are able to infect
different avian and mammalian animal hosts, from which they can be transmitted to humans …
different avian and mammalian animal hosts, from which they can be transmitted to humans …
Theoretical basis of the test-negative study design for assessment of influenza vaccine effectiveness
Influenza viruses undergo frequent antigenic changes. As a result, the viruses circulating
change within and between seasons, and the composition of the influenza vaccine is …
change within and between seasons, and the composition of the influenza vaccine is …
Evolutionary consequences of drug resistance: shared principles across diverse targets and organisms
Drug therapy has a crucial role in the treatment of viral, bacterial, fungal and protozoan
infections, as well as the control of human cancer. The success of therapy is being …
infections, as well as the control of human cancer. The success of therapy is being …
Antithrombotic therapy in patients with COVID-19?-Rationale and Evidence
In patients with severe or critical Coronavirus disease 2019 (COVID-19) manifestations, a
thromboinflammatory syndrome, with diffuse microvascular thrombosis, is increasingly …
thromboinflammatory syndrome, with diffuse microvascular thrombosis, is increasingly …
Clinical implications of antiviral resistance in influenza
Influenza is a major cause of severe respiratory infections leading to excessive
hospitalizations and deaths globally; annual epidemics, pandemics, and sporadic/endemic …
hospitalizations and deaths globally; annual epidemics, pandemics, and sporadic/endemic …
The epidemiology and spread of drug resistant human influenza viruses
Highlights•Changes in the circulation of antiviral-resistant influenza viruses have
occurred.•All human influenza viruses are currently resistant to the adamantanes.•Little …
occurred.•All human influenza viruses are currently resistant to the adamantanes.•Little …
Platelet activation and aggregation promote lung inflammation and influenza virus pathogenesis
Rationale: The hallmark of severe influenza virus infection is excessive inflammation of the
lungs. Platelets are activated during influenza, but their role in influenza virus pathogenesis …
lungs. Platelets are activated during influenza, but their role in influenza virus pathogenesis …
[HTML][HTML] Global update on the susceptibility of human influenza viruses to neuraminidase inhibitors, 2013–2014
Abstract Four World Health Organization (WHO) Collaborating Centres for Reference and
Research on Influenza and one WHO Collaborating Centre for the Surveillance …
Research on Influenza and one WHO Collaborating Centre for the Surveillance …
Neuraminidase inhibitor resistance in influenza: a clinical perspective
These findings highlight the importance of continuous surveillance, and assessment of viral
fitness and transmissibility of resistant virus strains. Detection can be challenging, especially …
fitness and transmissibility of resistant virus strains. Detection can be challenging, especially …