Research advances in BODIPY-assembled supramolecular photosensitizers for photodynamic therapy

J Wang, Q Gong, L Jiao, E Hao - Coordination Chemistry Reviews, 2023 - Elsevier
Photodynamic therapy (PDT) is a promising therapeutic approach for anticancer and
antibacterial treatment via photoinduced reactive oxygen species (ROS) generation …

Evolution of BODIPY as triplet photosensitizers from homogeneous to heterogeneous: The strategies of functionalization to various forms and their recent applications

D Wang, X Wang, S Zhou, P Gu, X Zhu, C Wang… - Coordination Chemistry …, 2023 - Elsevier
The BODIPY chromophore is one of the most versatile fluorophore building blocks in various
research fields, especially in life science and material science. It has attracted substantial …

Supramolecular photosensitizer enables oxygen-independent generation of hydroxyl radicals for photodynamic therapy

KX Teng, LY Niu, QZ Yang - Journal of the American Chemical …, 2023 - ACS Publications
The highly oxygen-dependent nature of photodynamic therapy (PDT) limits its therapeutic
efficacy against hypoxic solid tumors in clinics, which is an urgent problem to be solved …

Oxygen-independent organic photosensitizer with ultralow-power NIR photoexcitation for tumor-specific photodynamic therapy

Y Tang, Y Li, B Li, W Song, G Qi, J Tian… - Nature …, 2024 - nature.com
Photodynamic therapy (PDT) is a promising cancer treatment but has limitations due to its
dependence on oxygen and high-power-density photoexcitation. Here, we report polymer …

Augmenting cancer therapy with a supramolecular immunogenic cell death inducer: A lysosome-targeted NIR-light-activated ruthenium (II) metallacycle

L Tu, C Li, Q Ding, A Sharma, M Li, J Li… - Journal of the …, 2024 - ACS Publications
Though immunogenic cell death (ICD) has garnered significant attention in the realm of
anticancer therapies, effectively stimulating strong immune responses with minimal side …

M−N3 Configuration on Boron Nitride Boosts Singlet Oxygen Generation via Peroxymonosulfate Activation for Selective Oxidation

J Zhen, J Sun, X Xu, Z Wu, W Song… - Angewandte Chemie …, 2024 - Wiley Online Library
Abstract Singlet oxygen (1O2) is an essential reactive species responsible for selective
oxidation of organic matter, especially in Fenton‐like processes. However, due to the great …

Engineered metallacycle‐based supramolecular Photosensitizers for effective Photodynamic Therapy

L Tu, C Li, X **ong, J Hyeon Kim, Q Li, L Mei… - Angewandte …, 2023 - Wiley Online Library
Although metallacycle‐based supramolecular photosensitizers (PSs) have attracted
increasing attention in biomedicine, their clinical translation is still hindered by their inherent …

Thymoquinone as an electron transfer mediator to convert Type II photosensitizers to Type I photosensitizers

J Zhuang, G Qi, Y Feng, M Wu, H Zhang… - Nature …, 2024 - nature.com
The development of Type I photosensitizers (PSs) is of great importance due to the inherent
hypoxic intolerance of photodynamic therapy (PDT) in the hypoxic microenvironment …

Recent advances in type I organic photosensitizers for efficient photodynamic therapy for overcoming tumor hypoxia

B Lu, L Wang, H Tang, D Cao - Journal of Materials Chemistry B, 2023 - pubs.rsc.org
Photodynamic therapy (PDT) with an oxygen-dependent character is a noninvasive
therapeutic method for cancer treatment. However, its clinical therapeutic effect is greatly …

Photo‐Induced Disproportionation‐Mediated Photodynamic Therapy: Simultaneous Oxidation of Tetrahydrobiopterin and Generation of Superoxide Radicals

KX Teng, D Zhang, BK Liu, ZF Liu, LY Niu… - Angewandte …, 2024 - Wiley Online Library
We herein present an approach of photo‐induced disproportionation for preparation of Type‐
I photodynamic agents. As a proof of concept, BODIPY‐based photosensitizers were …