Zwitterionic biomaterials

Q Li, C Wen, J Yang, X Zhou, Y Zhu, J Zheng… - Chemical …, 2022 - ACS Publications
The term “zwitterionic polymers” refers to polymers that bear a pair of oppositely charged
groups in their repeating units. When these oppositely charged groups are equally …

Shining new light on biological systems: luminescent transition metal complexes for bioimaging and biosensing applications

LCC Lee, KKW Lo - Chemical Reviews, 2024 - ACS Publications
Luminescence imaging is a powerful and versatile technique for investigating cell
physiology and pathology in living systems, making significant contributions to life science …

Nrf2/Keap1/ARE signaling: Towards specific regulation

AV Ulasov, AA Rosenkranz, GP Georgiev, AS Sobolev - Life sciences, 2022 - Elsevier
The Nrf2 transcription factor governs the expression of hundreds genes involved in cell
defense against oxidative stress, the hallmark of numerous diseases such as …

Trends in peptide drug discovery

M Muttenthaler, GF King, DJ Adams… - Nature reviews Drug …, 2021 - nature.com
Since the introduction of insulin almost a century ago, more than 80 peptide drugs have
reached the market for a wide range of diseases, including diabetes, cancer, osteoporosis …

[HTML][HTML] On a highway to the brain: A review on nose-to-brain drug delivery using nanoparticles

ML Formica, DA Real, ML Picchio, E Catlin… - Applied Materials …, 2022 - Elsevier
The administration of drugs to the central nervous system (CNS) is primarily controlled by
the blood-brain barrier (BBB), a structure that prevents the passage of foreign compounds …

Protein nanoparticles in drug delivery: animal protein, plant proteins and protein cages, albumin nanoparticles

E Kianfar - Journal of Nanobiotechnology, 2021 - Springer
In this article, we will describe the properties of albumin and its biological functions, types of
sources that can be used to produce albumin nanoparticles, methods of producing albumin …

Designing bioresponsive nanomaterials for intracellular self-assembly

S Chagri, DYW Ng, T Weil - Nature Reviews Chemistry, 2022 - nature.com
Supramolecular assemblies are essential components of living organisms. Cellular
scaffolds, such as the cytoskeleton or the cell membrane, are formed via secondary …

Design, optimization, and nanotechnology of antimicrobial peptides: From exploration to applications

P Tan, H Fu, X Ma - Nano Today, 2021 - Elsevier
Antibiotic resistance caused by antibiotic abuse, especially the emergence of multi-drug
resistant bacteria, poses a serious threat to human health, and makes it imperative to find …

Concepts of nanoparticle cellular uptake, intracellular trafficking, and kinetics in nanomedicine

ND Donahue, H Acar, S Wilhelm - Advanced drug delivery reviews, 2019 - Elsevier
Nanoparticle-based therapeutics and diagnostics are commonly referred to as
nanomedicine and may significantly impact the future of healthcare. However, the clinical …

Surface-enhanced Raman spectroscopy for bioanalysis: reliability and challenges

C Zong, M Xu, LJ Xu, T Wei, X Ma, XS Zheng… - Chemical …, 2018 - ACS Publications
Surface-enhanced Raman spectroscopy (SERS) inherits the rich chemical fingerprint
information on Raman spectroscopy and gains sensitivity by plasmon-enhanced excitation …