Human immunology through the lens of evolutionary genetics
L Quintana-Murci - Cell, 2019 - cell.com
Pathogen-imposed selection pressures have been paramount during human evolution.
Detecting such selection signatures in ancient and modern human genomes can thus help …
Detecting such selection signatures in ancient and modern human genomes can thus help …
Middle to late holocene paleoclimatic change and the early bantu expansion in the rain forests of Western Central Africa
K Bostoen, B Clist, C Doumenge… - Current …, 2015 - journals.uchicago.edu
This article reviews evidence from biogeography, palynology, geology, historical linguistics,
and archaeology and presents a new synthesis of the paleoclimatic context in which the …
and archaeology and presents a new synthesis of the paleoclimatic context in which the …
High-depth African genomes inform human migration and health
The African continent is regarded as the cradle of modern humans and African genomes
contain more genetic variation than those from any other continent, yet only a fraction of the …
contain more genetic variation than those from any other continent, yet only a fraction of the …
[HTML][HTML] Genetic adaptation and neandertal admixture shaped the immune system of human populations
H Quach, M Rotival, J Pothlichet, YHE Loh… - Cell, 2016 - cell.com
Humans differ in the outcome that follows exposure to life-threatening pathogens, yet the
extent of population differences in immune responses and their genetic and evolutionary …
extent of population differences in immune responses and their genetic and evolutionary …
The African genome variation project shapes medical genetics in Africa
Given the importance of Africa to studies of human origins and disease susceptibility,
detailed characterization of African genetic diversity is needed. The African Genome …
detailed characterization of African genetic diversity is needed. The African Genome …
Dispersals and genetic adaptation of Bantu-speaking populations in Africa and North America
Bantu languages are spoken by about 310 million Africans, yet the genetic history of Bantu-
speaking populations remains largely unexplored. We generated genomic data for 1318 …
speaking populations remains largely unexplored. We generated genomic data for 1318 …
Uganda genome resource enables insights into population history and genomic discovery in Africa
Genomic studies in African populations provide unique opportunities to understand disease
etiology, human diversity, and population history. In the largest study of its kind, comprising …
etiology, human diversity, and population history. In the largest study of its kind, comprising …
Genomic perspectives on human dispersals during the Holocene
Nearly 20 y ago, Jared Diamond and Peter Bellwood reviewed the evidence for the
associated spread of farming and large language families by the demographic expansions …
associated spread of farming and large language families by the demographic expansions …
Inferring population size history from large samples of genome-wide molecular data-an approximate Bayesian computation approach
Inferring the ancestral dynamics of effective population size is a long-standing question in
population genetics, which can now be tackled much more accurately thanks to the massive …
population genetics, which can now be tackled much more accurately thanks to the massive …
Tales of human migration, admixture, and selection in Africa
In the last three decades, genetic studies have played an increasingly important role in
exploring human history. They have helped to conclusively establish that anatomically …
exploring human history. They have helped to conclusively establish that anatomically …