Drivers of microbiome biodiversity: a review of general rules, feces, and ignorance

AT Reese, RR Dunn - MBio, 2018 - Am Soc Microbiol
The alpha diversity of ecologic communities is affected by many biotic and abiotic drivers
and, in turn, affects ecosystem functioning. Yet, patterns of alpha diversity in host-associated …

Not all animals need a microbiome

TJ Hammer, JG Sanders, N Fierer - FEMS microbiology letters, 2019 - academic.oup.com
It is often taken for granted that all animals host and depend upon a microbiome, yet this has
only been shown for a small proportion of species. We propose that animals span a …

Multi-kingdom ecological drivers of microbiota assembly in preterm infants

C Rao, KZ Coyte, W Bainter, RS Geha, CR Martin… - Nature, 2021 - nature.com
The gut microbiota of preterm infants develops predictably,,,,,–, with pioneer species
colonizing the gut after birth, followed by an ordered succession of microorganisms. The gut …

[HTML][HTML] Colonization of the live biotherapeutic product VE303 and modulation of the microbiota and metabolites in healthy volunteers

M Dsouza, R Menon, E Crossette, SK Bhattarai… - Cell Host & Microbe, 2022 - cell.com
Manipulation of the gut microbiota via fecal microbiota transplantation (FMT) has shown
clinical promise in diseases such as recurrent Clostridioides difficile infection (rCDI) …

Microbiotas from humans with inflammatory bowel disease alter the balance of gut Th17 and RORγt+ regulatory T cells and exacerbate colitis in mice

GJ Britton, EJ Contijoch, I Mogno, OH Vennaro… - Immunity, 2019 - cell.com
Microbiota are thought to influence the development and progression of inflammatory bowel
disease (IBD), but determining generalizable effects of microbiota on IBD etiology requires …

Quantitative PCR provides a simple and accessible method for quantitative microbiota profiling

C Jian, P Luukkonen, H Yki-Järvinen, A Salonen… - PloS one, 2020 - journals.plos.org
The use of relative abundance data from next generation sequencing (NGS) can lead to
misinterpretations of microbial community structures, as the increase of one taxon leads to …

Precise quantification of bacterial strains after fecal microbiota transplantation delineates long-term engraftment and explains outcomes

V Aggarwala, I Mogno, Z Li, C Yang, GJ Britton… - Nature …, 2021 - nature.com
Fecal microbiota transplantation (FMT) has been successfully applied to treat recurrent
Clostridium difficile infection in humans, but a precise method to measure which bacterial …

Fecal IgA levels are determined by strain-level differences in Bacteroides ovatus and are modifiable by gut microbiota manipulation

C Yang, I Mogno, EJ Contijoch, JN Borgerding… - Cell host & …, 2020 - cell.com
Fecal IgA production depends on colonization by a gut microbiota. However, the bacterial
strains that drive gut IgA production remain largely unknown. Here, we assessed the IgA …

Ecophysiology and interactions of a taurine-respiring bacterium in the mouse gut

H Ye, S Borusak, C Eberl, J Krasenbrink… - Nature …, 2023 - nature.com
Taurine-respiring gut bacteria produce H2S with ambivalent impact on host health. We
report the isolation and ecophysiological characterization of a taurine-respiring mouse gut …

Evolutionary and ecological consequences of gut microbial communities

NA Moran, H Ochman… - Annual Review of Ecology …, 2019 - annualreviews.org
Animals are distinguished by having guts—organs that must extract nutrients from food yet
also bar invasion by pathogens. Most guts are colonized by nonpathogenic microorganisms …