Cellular and molecular mechanisms of skin wound healing
Wound healing is a complex process that involves the coordinated actions of many different
tissues and cell lineages. It requires tight orchestration of cell migration, proliferation, matrix …
tissues and cell lineages. It requires tight orchestration of cell migration, proliferation, matrix …
Pathophysiology of RAGE in inflammatory diseases
H Dong, Y Zhang, Y Huang, H Deng - Frontiers in Immunology, 2022 - frontiersin.org
The receptor for advanced glycation end products (RAGE) is a non-specific multi-ligand
pattern recognition receptor capable of binding to a range of structurally diverse ligands …
pattern recognition receptor capable of binding to a range of structurally diverse ligands …
Fueling the fire: inflammatory forms of cell death and implications for cancer immunotherapy
Unleashing the immune system with immune checkpoint inhibitors (ICI) has significantly
improved overall survival for subsets of patients with stage III/IV cancer. However, many …
improved overall survival for subsets of patients with stage III/IV cancer. However, many …
Targeting RAGE signaling in inflammatory disease
BI Hudson, ME Lippman - Annual review of medicine, 2018 - annualreviews.org
The receptor for advanced glycation end-products (RAGE) is a multiligand pattern
recognition receptor implicated in diverse chronic inflammatory states. RAGE binds and …
recognition receptor implicated in diverse chronic inflammatory states. RAGE binds and …
Receptor for advanced glycation end products (RAGE) and mechanisms and therapeutic opportunities in diabetes and cardiovascular disease: insights from human …
Obesity and diabetes are leading causes of cardiovascular morbidity and mortality. Although
extensive strides have been made in the treatments for non-diabetic atherosclerosis and its …
extensive strides have been made in the treatments for non-diabetic atherosclerosis and its …
Targeting the receptor for advanced glycation endproducts (RAGE): a medicinal chemistry perspective
S Bongarzone, V Savickas, F Luzi… - Journal of medicinal …, 2017 - ACS Publications
The receptor for advanced glycation endproducts (RAGE) is an ubiquitous, transmembrane,
immunoglobulin-like receptor that exists in multiple isoforms and binds to a diverse range of …
immunoglobulin-like receptor that exists in multiple isoforms and binds to a diverse range of …
Cellular signalling of the receptor for advanced glycation end products (RAGE)
J **e, JD Méndez, V Méndez-Valenzuela… - Cellular signalling, 2013 - Elsevier
The receptor for advanced glycation end-product (RAGE) is the signal transduction receptor
which senses a variety of signalling molecules including advanced glycation end products …
which senses a variety of signalling molecules including advanced glycation end products …
Mechanistic targeting of advanced glycation end-products in age-related diseases
S Rowan, E Bejarano, A Taylor - … et Biophysica Acta (BBA)-Molecular Basis …, 2018 - Elsevier
Glycative stress, caused by the accumulation of cytotoxic and irreversibly-formed sugar-
derived advanced glycation end-products (AGEs), contributes to morbidity associated with …
derived advanced glycation end-products (AGEs), contributes to morbidity associated with …
HMGB1 and RAGE in inflammation and cancer
GP Sims, DC Rowe, ST Rietdijk… - Annual review of …, 2009 - annualreviews.org
The immune system has evolved to respond not only to pathogens, but also to signals
released from dying cells. Cell death through necrosis induces inflammation, whereas …
released from dying cells. Cell death through necrosis induces inflammation, whereas …
Receptor for AGE (RAGE): signaling mechanisms in the pathogenesis of diabetes and its complications
R Ramasamy, SF Yan… - Annals of the New York …, 2011 - Wiley Online Library
The receptor for advanced glycation endproducts (RAGE) was first described as a signal
transduction receptor for advanced glycation endproducts (AGEs), the products of …
transduction receptor for advanced glycation endproducts (AGEs), the products of …