Cellular and molecular mechanisms of skin wound healing

OA Peña, P Martin - Nature Reviews Molecular Cell Biology, 2024 - nature.com
Wound healing is a complex process that involves the coordinated actions of many different
tissues and cell lineages. It requires tight orchestration of cell migration, proliferation, matrix …

Pathophysiology of RAGE in inflammatory diseases

H Dong, Y Zhang, Y Huang, H Deng - Frontiers in Immunology, 2022 - frontiersin.org
The receptor for advanced glycation end products (RAGE) is a non-specific multi-ligand
pattern recognition receptor capable of binding to a range of structurally diverse ligands …

Fueling the fire: inflammatory forms of cell death and implications for cancer immunotherapy

SR Rosenbaum, NA Wilski, AE Aplin - Cancer discovery, 2021 - AACR
Unleashing the immune system with immune checkpoint inhibitors (ICI) has significantly
improved overall survival for subsets of patients with stage III/IV cancer. However, many …

Targeting RAGE signaling in inflammatory disease

BI Hudson, ME Lippman - Annual review of medicine, 2018 - annualreviews.org
The receptor for advanced glycation end-products (RAGE) is a multiligand pattern
recognition receptor implicated in diverse chronic inflammatory states. RAGE binds and …

Targeting the receptor for advanced glycation endproducts (RAGE): a medicinal chemistry perspective

S Bongarzone, V Savickas, F Luzi… - Journal of medicinal …, 2017 - ACS Publications
The receptor for advanced glycation endproducts (RAGE) is an ubiquitous, transmembrane,
immunoglobulin-like receptor that exists in multiple isoforms and binds to a diverse range of …

Cellular signalling of the receptor for advanced glycation end products (RAGE)

J **e, JD Méndez, V Méndez-Valenzuela… - Cellular signalling, 2013 - Elsevier
The receptor for advanced glycation end-product (RAGE) is the signal transduction receptor
which senses a variety of signalling molecules including advanced glycation end products …

Mechanistic targeting of advanced glycation end-products in age-related diseases

S Rowan, E Bejarano, A Taylor - … et Biophysica Acta (BBA)-Molecular Basis …, 2018 - Elsevier
Glycative stress, caused by the accumulation of cytotoxic and irreversibly-formed sugar-
derived advanced glycation end-products (AGEs), contributes to morbidity associated with …

HMGB1 and RAGE in inflammation and cancer

GP Sims, DC Rowe, ST Rietdijk… - Annual review of …, 2009 - annualreviews.org
The immune system has evolved to respond not only to pathogens, but also to signals
released from dying cells. Cell death through necrosis induces inflammation, whereas …

Receptor for AGE (RAGE): signaling mechanisms in the pathogenesis of diabetes and its complications

R Ramasamy, SF Yan… - Annals of the New York …, 2011 - Wiley Online Library
The receptor for advanced glycation endproducts (RAGE) was first described as a signal
transduction receptor for advanced glycation endproducts (AGEs), the products of …