Synthesis and transformations of nitrones for organic synthesis

SI Murahashi, Y Imada - Chemical reviews, 2019 - ACS Publications
Nitrones are important compounds and are highly useful in many aspects. The first part
describes the methods for synthesis of nitrones, which are useful and environmentally …

Mechanochemical organic synthesis

GW Wang - Chemical Society Reviews, 2013 - pubs.rsc.org
Recently, mechanical milling using a mixer mill or planetary mill has been fruitfully utilized in
organic synthesis under solvent-free conditions. This review article provides a …

Mechanochemistry: A force in disguise and conditional effects towards chemical reactions

S Mateti, M Mathesh, Z Liu, T Tao… - Chemical …, 2021 - pubs.rsc.org
Mechanochemistry refers to unusual chemical reactions induced by mechanical energy at
room temperatures. It has attracted increased attention because of advantages, such as …

Ball milling in organic synthesis: solutions and challenges

A Stolle, T Szuppa, SES Leonhardt… - Chemical Society …, 2011 - pubs.rsc.org
During the last decade numerous protocols have been published using the method of ball
milling for synthesis all over the field of organic chemistry. However, compared to other …

Solvent-free Sonogashira coupling reaction via high speed ball milling

DA Fulmer, WC Shearouse, ST Medonza, J Mack - Green Chemistry, 2009 - pubs.rsc.org
Herein, we report on the solvent-free Sonogashira reaction utilizing high speed ball milling.
Sonogashira coupling of a variety of para substituted aryl halides were performed with …

Controlling reactivity through liquid assisted grinding: the curious case of mechanochemical fluorination

JL Howard, Y Sagatov, L Repusseau, C Schotten… - Green …, 2017 - pubs.rsc.org
We have identified an example of a mechanochemically milled organic reaction where liquid-
assisted grinding controls the selectivity, such a phenomenon has not been …

Fast copper-, ligand-and solvent-free Sonogashira coupling in a ball mill

R Thorwirth, A Stolle, B Ondruschka - Green Chemistry, 2010 - pubs.rsc.org
A solvent-free method for the Sonogashira coupling reaction was established under ball
milling conditions without the use of copper or additional ligands. Pd (OAc) 2 or Pd (PPh3) 4 …

Solvent-free cross-dehydrogenative coupling reactions under high speed ball-milling conditions applied to the synthesis of functionalized tetrahydroisoquinolines

W Su, J Yu, Z Li, Z Jiang - The Journal of Organic Chemistry, 2011 - ACS Publications
Solvent-free reaction using a high-speed ball milling technique has been first applied to
cross-dehydrogenative coupling (CDC) reactions between tetrahydroisoquinolines and …

Synthesis of molecular nanostructures by multicomponent condensation reactions in a ball mill

B Içli, N Christinat, J Tönnemann… - Journal of the …, 2009 - ACS Publications
Synthesis of Molecular Nanostructures by Multicomponent Condensation Reactions in a Ball
Mill | Journal of the American Chemical Society Recently Viewedclose modal ACS ACS …

Mechanochemical preparation of hydantoins from amino esters: application to the synthesis of the antiepileptic drug phenytoin

L Konnert, B Reneaud, RM de Figueiredo… - The Journal of …, 2014 - ACS Publications
The eco-friendly preparation of 5-and 5, 5-disubstituted hydantoins from various amino ester
hydrochlorides and potassium cyanate in a planetary ball-mill is described. The one-pot/two …