Extracellular vesicles: a rising star for therapeutics and drug delivery

S Du, Y Guan, A ** and navigation of microrobots in the mouse brain vasculature
A Del Campo Fonseca, C Glück, J Droux… - Nature …, 2023 - nature.com
The intricate and delicate anatomy of the brain poses significant challenges for the treatment
of cerebrovascular and neurodegenerative diseases. Thus, precise local drug delivery in …

[HTML][HTML] Engineered mesenchymal stem cell-derived extracellular vesicles: a state-of-the-art multifunctional weapon against Alzheimer's disease

T Yin, Y Liu, W Ji, J Zhuang, X Chen, B Gong, J Chu… - Theranostics, 2023 - ncbi.nlm.nih.gov
With the increase of population aging, the number of Alzheimer's disease (AD) patients is
also increasing. According to current estimates, approximately 11% of people over 65 suffer …

Engineering therapeutical extracellular vesicles for clinical translation

Y Ma, S Dong, AJ Grippin, L Teng, AS Lee… - Trends in …, 2024 - cell.com
Cell-based therapies are revolutionizing medicine by replacing or modifying dysfunctional
cells with healthy cells or engineered derivatives, offering disease reversal and cure. One …

Acoustic separation and concentration of exosomes for nucleotide detection: ASCENDx

TD Naquin, AJ Canning, Y Gu, J Chen, CM Naquin… - Science …, 2024 - science.org
Efficient isolation and analysis of exosomal biomarkers hold transformative potential in
biomedical applications. However, current methods are prone to contamination and require …

Methodologies, technologies, and strategies for acoustic streaming-based acoustofluidics

M Stringer, Z Zeng, X Zhang, Y Chai, W Li… - Applied Physics …, 2023 - pubs.aip.org
Acoustofluidics offers contact-free manipulation of particles and fluids, enabling their uses in
various life sciences, such as for biological and medical applications. Recently, there have …

Ultrasound robotics for precision therapy

ADC Fonseca, D Ahmed - Advanced Drug Delivery Reviews, 2024 - Elsevier
In recent years, the application of microrobots in precision therapy has gained significant
attention. The small size and maneuverability of these micromachines enable them to …

An acoustofluidic device for the automated separation of platelet-reduced plasma from whole blood

Z Ma, J **a, N Upreti, E David, J Rufo, Y Gu… - Microsystems & …, 2024 - nature.com
Separating plasma from whole blood is an important sample processing technique required
for fundamental biomedical research, medical diagnostics, and therapeutic applications …

A comprehensive review of challenges and advances in exosome-based drug delivery systems

SS Palakurthi, B Shah, S Kapre, N Charbe… - Nanoscale …, 2024 - pubs.rsc.org
Exosomes or so-called natural nanoparticles have recently shown enormous potential for
targeted drug delivery systems. Several studies have reported that exosomes as advanced …