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Methods and compositions for targeted genetic modification using paired guide RNAs
D Frendewey, KV Lai, W Auerbach, G Droguett… - US Patent …, 2019 - Google Patents
2017-03-07 Assigned to REGENERON PHARMACEUTICALS, INC. reassignment
REGENERON PHARMACEUTICALS, INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE …
REGENERON PHARMACEUTICALS, INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE …
Chemically modified guide RNAs for CRISPR/CAS-mediated gene regulation
Provided herein are methods for inducing CRISPR/Cas based gene regulation (eg, genome
editing or gene expres sion) of a target nucleic acid (eg, target DNA or target RNA) in a cell …
editing or gene expres sion) of a target nucleic acid (eg, target DNA or target RNA) in a cell …
CRISPR/CAS-related methods and compositions for treating sickle cell disease
AE Friedland, ML Maeder, GG Welstead… - US Patent …, 2022 - Google Patents
US11242525B2 - CRISPR/CAS-related methods and compositions for treating sickle cell
disease - Google Patents US11242525B2 - CRISPR/CAS-related methods and …
disease - Google Patents US11242525B2 - CRISPR/CAS-related methods and …
T: A TO A: T base editing through adenosine methylation
2021-09-02 Assigned to PRESIDENT AND FELLOWS OF HARVARD COLLEGE
reassignment PRESIDENT AND FELLOWS OF HARVARD COLLEGE ASSIGNMENT OF …
reassignment PRESIDENT AND FELLOWS OF HARVARD COLLEGE ASSIGNMENT OF …
Evaluation of Cas9 molecule/guide RNA molecule complexes
H Jayaram, W SELLECK - US Patent 11,180,793, 2021 - Google Patents
KMASKRIRDRONCR-JEDNCBNOSA-N O= C [C@ H]([U]) O [C@@ H](C= O) CO Chemical
compound O= C [C@ H]([U]) O [C@@ H](C= O) CO KMASKRIRDRONCR-JEDNCBNOSA-N …
compound O= C [C@ H]([U]) O [C@@ H](C= O) CO KMASKRIRDRONCR-JEDNCBNOSA-N …
Modified crispr rna and modified single crispr rna and uses thereof
M Rahdar, TP Prakash, EE Swayze, FC Bennett - 2017 - Google Patents
WO2017004261A1 - Modified crispr rna and modified single crispr rna and uses thereof -
Google Patents WO2017004261A1 - Modified crispr rna and modified single crispr rna and …
Google Patents WO2017004261A1 - Modified crispr rna and modified single crispr rna and …
Methods and products for genetic engineering
2018-06-19 Assigned to ECOLE NORMALE SUPERIEURE DE LYON, UNIVERSITE
CLAUDE BERNARD LYON 1, INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE …
CLAUDE BERNARD LYON 1, INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE …
CRISPR/Cas-related methods and compositions for treating Usher syndrome and retinitis pigmentosa
ML Maeder, DA Bumcrot - US Patent 11,028,388, 2021 - Google Patents
KMASKRIRDRONCR-JEDNCBNOSA-N O= C [C@ H]([U]) O [C@@ H](C= O) CO Chemical
compound O= C [C@ H]([U]) O [C@@ H](C= O) CO KMASKRIRDRONCR-JEDNCBNOSA-N …
compound O= C [C@ H]([U]) O [C@@ H](C= O) CO KMASKRIRDRONCR-JEDNCBNOSA-N …
Materials and methods for treatment of autosomal dominant retinitis pigmentosa
A Kantardzhieva, A Noma, A Scaria… - US Patent …, 2020 - Google Patents
US10662425B2 - Materials and methods for treatment of autosomal dominant retinitis
pigmentosa - Google Patents US10662425B2 - Materials and methods for treatment of …
pigmentosa - Google Patents US10662425B2 - Materials and methods for treatment of …
Mitochondrial genome editing and regulation
US11208652B2 - Mitochondrial genome editing and regulation - Google Patents US11208652B2
- Mitochondrial genome editing and regulation - Google Patents Mitochondrial genome editing …
- Mitochondrial genome editing and regulation - Google Patents Mitochondrial genome editing …