Mining the Biosynthetic Potential for Specialized Metabolism of a Streptomyces Soil Community

M Nicault, AR Tidjani, A Gauthier, S Dumarcay… - Antibiotics, 2020 - mdpi.com
The diversity and distribution of specialized metabolite gene clusters within a community of
bacteria living in the same soil habitat are poorly documented. Here we analyzed the …

Genome mining for drug discovery: Cyclic lipopeptides related to daptomycin

RH Baltz - Journal of Industrial Microbiology and Biotechnology, 2021 - academic.oup.com
The cyclic lipopeptide antibiotics structurally related to daptomycin were first reported in the
1950s. Several have common lipopeptide initiation, elongation, and termination …

Investigation of Streptomyces sp. Strain EMB24 Secondary Metabolite Profile Has Unraveled Its Extraordinary Antibacterial Potency Against Drug-Resistant Bacteria

N Goel, R Singh, S Sood, SK Khare - Marine Biotechnology, 2022 - Springer
With the overuse and misuse of antibiotics amid COVID-19 pandemic, the antimicrobial
resistance, which is already a global challenge, has accelerated its pace significantly …

Isolation, purification, and physio-chemical characterization of melanin pigment from nigerseed hulls (Guizotia abyssinica)

SK BT, UH Hebbar… - Preparative Biochemistry …, 2024 - Taylor & Francis
Plant melanin, a natural pigment, has gained significant attention recently due to its potential
therapeutic and industrial applications. In this study, melanin pigments were extracted from …

[HTML][HTML] Potential secondary metabolite from Indonesian Actinobacteria (InaCC A758) against Mycobacterium tuberculosis

MD Rakhmawatie, T Wibawa, P Lisdiyanti… - Iranian Journal of …, 2021 - ncbi.nlm.nih.gov
Objective (s): This study explored Indonesian Actinobacteria which were isolated from
Curcuma zedoaria endophytic microbes and mangrove ecosystem for new …

Social wasp-associated Tsukamurella sp. strains showed promising biosynthetic and bioactive potential for discovery of novel compounds

D Rojas-Villalta, K Núñez-Montero… - Scientific Reports, 2024 - nature.com
In the face of escalating antibiotic resistance, the quest for novel antimicrobial compounds is
critical. Actinobacteria is known for producing a substantial fraction of bioactive molecules …

[HTML][HTML] A genome-wide analysis of antibiotic producing genes in Streptomyces globisporus SP6C4

DR Kim, YS Kwak - The plant pathology journal, 2021 - ncbi.nlm.nih.gov
Soil is the major source of plant-associated microbes. Several fungal and bacterial species
live within plant tissues. Actinomycetes are well known for producing a variety of antibiotics …

Exploring the potential of antibiotic production from rare actinobacteria by whole-genome sequencing and guided MS/MS analysis

D Hu, C Sun, T **, G Fan, KM Mok, K Li… - Frontiers in …, 2020 - frontiersin.org
Actinobacteria are well recognized for their production of structurally diverse bioactive
secondary metabolites, but the rare actinobacterial genera have been underexploited for …

Genome analysis of the salt-resistant Paludifilum halophilum DSM 102817T reveals genes involved in flux-tuning of ectoines and unexplored bioactive secondary …

D Frikha-Dammak, H Ayadi, I Hakim-Rekik… - World Journal of …, 2021 - Springer
Paludifilum halophilum DSM 102817 T is the first member of the genus Paludifilum in the
Thermoactinomycetaceae family. The thermohalophilic bacterium was isolated from the …

[PDF][PDF] Cytotoxic and antimicrobial activities of microbial proteins from mangrove soil actinomycetes of Mangalore, Dakshina Kannada

Y Karthik, MI Kalyani, KS Sheethal, D Rakshitha… - …, 2020 - researchgate.net
ABSTRACT Introduction and Aim: Actinomycetes are Gram-positive microbes that share
characters of both bacteria and fungi, which are distributed uniformly across the world. The …