2024 AHA/ACC/AMSSM/HRS/PACES/SCMR guideline for the management of hypertrophic cardiomyopathy: a report of the American Heart Association/American …

Writing Committee Members, SR Ommen… - Journal of the American …, 2024 - jacc.org
Abstract Aim The “2024 AHA/ACC/AMSSM/HRS/PACES/SCMR Guideline for the
Management of Hypertrophic Cardiomyopathy” provides recommendations to guide …

2020 AHA/ACC guideline for the diagnosis and treatment of patients with hypertrophic cardiomyopathy: a report of the American College of Cardiology/American …

SR Ommen, S Mital, MA Burke, SM Day… - Journal of the American …, 2020 - jacc.org
The recommendations listed in this guideline are, whenever possible, evidence based. An
initial extensive evidence review, which included literature derived from research involving …

Efficient in vivo genome editing prevents hypertrophic cardiomyopathy in mice

D Reichart, GA Newby, H Wakimoto, M Lun… - Nature medicine, 2023 - nature.com
Dominant missense pathogenic variants in cardiac myosin heavy chain cause hypertrophic
cardiomyopathy (HCM), a currently incurable disorder that increases risk for stroke, heart …

Recommendations for participation in competitive and leisure time sport in athletes with cardiomyopathies, myocarditis, and pericarditis: position statement of the Sport …

A Pelliccia, EE Solberg, M Papadakis… - European Heart …, 2019 - academic.oup.com
Myocardial diseases are associated with an increased risk of potentially fatal cardiac
arrhythmias and sudden cardiac death/cardiac arrest during exercise, including hypertrophic …

Myosin sequestration regulates sarcomere function, cardiomyocyte energetics, and metabolism, informing the pathogenesis of hypertrophic cardiomyopathy

CN Toepfer, AC Garfinkel, G Venturini, H Wakimoto… - Circulation, 2020 - ahajournals.org
Background: Hypertrophic cardiomyopathy (HCM) is caused by pathogenic variants in
sarcomere protein genes that evoke hypercontractility, poor relaxation, and increased …

New perspectives on the prevalence of hypertrophic cardiomyopathy

C Semsarian, J Ingles, MS Maron, BJ Maron - Journal of the American …, 2015 - jacc.org
Hypertrophic cardiomyopathy (HCM) is an important genetic heart muscle disease for which
prevalence in the general population has not been completely resolved. For the past 20 …

A small-molecule inhibitor of sarcomere contractility suppresses hypertrophic cardiomyopathy in mice

EM Green, H Wakimoto, RL Anderson, MJ Evanchik… - Science, 2016 - science.org
Hypertrophic cardiomyopathy (HCM) is an inherited disease of heart muscle that can be
caused by mutations in sarcomere proteins. Clinical diagnosis depends on an abnormal …

Hypertrophic cardiomyopathy: present and future, with translation into contemporary cardiovascular medicine

BJ Maron, SR Ommen, C Semsarian, P Spirito… - Journal of the American …, 2014 - jacc.org
Hypertrophic cardiomyopathy (HCM) is a common inherited heart disease with diverse
phenotypic and genetic expression, clinical presentation, and natural history. HCM has been …

2011 ACCF/AHA guideline for the diagnosis and treatment of hypertrophic cardiomyopathy: a report of the American College of Cardiology Foundation/American …

BJ Gersh, BJ Maron, RO Bonow, JA Dearani… - Journal of the American …, 2011 - jacc.org
1.1. Methodology and Evidence Review The recommendations listed in this document are,
whenever possible, evidence based. An extensive evidence review was conducted through …

2011 ACCF/AHA guideline for the diagnosis and treatment of hypertrophic cardiomyopathy: executive summary: a report of the American College of Cardiology …

BJ Gersh, BJ Maron, RO Bonow, JA Dearani, MA Fifer… - Circulation, 2011 - ahajournals.org
The recommendations listed in this document are, whenever possible, evidence based. An
extensive evidence review was conducted through January 2011. Searches were limited to …