Microbes are hardly seen as planktonic species and are most commonly found as biofilm
communities in cases of chronic infections. Biofilms are regarded as a biological condition …

Antimicrobial resistance is a leading cause of mortality worldwide. Without newly approved
antibiotics and antifungals being brought to the market, resistance is being developed to the …

The quorum sensing (QS) circuit plays a role in the precise regulation of genes controlling
virulence factors and biofilm formation in Pseudomonas aeruginosa. QS-controlled biofilm …

Highlights•The identification of novel drug targets is a key step in drug innovation.•Essential
genes are vital for organism survival and are promising drug targets.•We describe in detail …

The nitrogen cycle pathways are responsible for the circulation of inorganic and organic N-
containing molecules in nature. Among these pathways, those involving amino acids, N …

Biofilm formation by Pseudomonas aeruginosa is primarily responsible for chronic wound
and lung infections in humans. These infections are persistent owing to the biofilm's high …

Biofilm-related infections substantially contribute to bacterial illnesses, with estimates
indicating that at least 80% of such diseases are linked to biofilms. Biofilms exhibit unique …

A hallmark of Pseudomonas aeruginosa is its ability to establish biofilm-based infections that
are difficult to eradicate. Biofilms are less susceptible to host inflammatory and immune …

S treptococcus gordonii is an oral commensal and an early coloniser of dental plaque. In
vitro, S. gordonii is conditionally auxotrophic for arginine in monoculture but biosynthesises …

Microorganisms acquire energy and nutrients from dynamic environments, where substrates
vary in both type and abundance. The regulatory system responsible for prioritizing …