The roles of gut microbiota and its metabolites in diabetic nephropathy
H Zhao, CE Yang, T Liu, MX Zhang, Y Niu… - Frontiers in …, 2023 - frontiersin.org
Diabetic nephropathy (DN) is a severe microvascular complication of diabetes, which
increases the risk of renal failure and causes a high global disease burden. Due to the lack …
increases the risk of renal failure and causes a high global disease burden. Due to the lack …
[HTML][HTML] Mycobacterium abscessus: It's Complex
HFM Abdelaal, ED Chan, L Young, SL Baldwin… - Microorganisms, 2022 - mdpi.com
Mycobacterium abscessus (M. abscessus) is an opportunistic pathogen usually colonizing
abnormal lung airways and is often seen in patients with cystic fibrosis. Currently, there is no …
abnormal lung airways and is often seen in patients with cystic fibrosis. Currently, there is no …
Noncanonical autophagy is a new strategy to inhibit HSV-1 through STING1 activation
Z Zheng, M Zhao, H Shan, D Fang, Z **, J Tang, Z Liu… - Autophagy, 2023 - Taylor & Francis
ABSTRACT STING1 (stimulator of interferon response cGAMP interactor 1) plays an
essential role in immune responses for virus inhibition via inducing the production of type I …
essential role in immune responses for virus inhibition via inducing the production of type I …
[HTML][HTML] Autophagy: guardian of skin barrier
HJ Kim, J Park, SK Kim, H Park, JE Kim, S Lee - Biomedicines, 2022 - mdpi.com
Autophagy is a major degradation pathway that removes harmful intracellular substances to
maintain homeostasis. Various stressors, such as starvation and oxidative stress, upregulate …
maintain homeostasis. Various stressors, such as starvation and oxidative stress, upregulate …
Dimethyl itaconate is effective in host-directed antimicrobial responses against mycobacterial infections through multifaceted innate immune pathways
YJ Kim, EJ Park, SH Lee, P Silwal, JK Kim, JS Yang… - Cell & Bioscience, 2023 - Springer
Background Itaconate, a crucial immunometabolite, plays a critical role in linking immune
and metabolic functions to influence host defense and inflammation. Due to its polar …
and metabolic functions to influence host defense and inflammation. Due to its polar …
Association of gut microbiota with intestinal ischemia/reperfusion injury
J Chen, Y Wang, Y Shi, Y Liu, C Wu… - Frontiers in Cellular and …, 2022 - frontiersin.org
Intestinal ischemia/reperfusion (II/R) is a common acute and critical condition in clinical
practice with a high mortality rate. However, there is still a lack of effective prevention and …
practice with a high mortality rate. However, there is still a lack of effective prevention and …
DRAM1 Promotes Lysosomal Delivery of Mycobacterium marinum in Macrophages
A Banducci-Karp, J **e, SAG Engels, C Sarantaris… - Cells, 2023 - mdpi.com
Damage-Regulated Autophagy Modulator 1 (DRAM1) is an infection-inducible membrane
protein, whose function in the immune response is incompletely understood. Based on …
protein, whose function in the immune response is incompletely understood. Based on …
Host-directed therapy with amiodarone in preclinical models restricts mycobacterial infection and enhances autophagy
G Kilinç, R Boland, MT Heemskerk… - Microbiology …, 2024 - journals.asm.org
Mycobacterium tuberculosis (Mtb) as well as nontuberculous mycobacteria are intracellular
pathogens whose treatment is extensive and increasingly impaired due to the rise of …
pathogens whose treatment is extensive and increasingly impaired due to the rise of …
TRAF6 triggers Mycobacterium-infected host autophagy through Rab7 ubiquitination
Q Ma, J Yu, L Liu, X Ma, J Zhang, J Zhang… - Cell Death …, 2023 - nature.com
Tumor necrosis factor receptor-associated factor 6 (TRAF6) is an E3 ubiquitin ligase that is
extensively involved in the autophagy process by interacting with diverse autophagy …
extensively involved in the autophagy process by interacting with diverse autophagy …
Evaluation and clinical impact of MALDI Biotyper Mycobacteria Library v6. 0 for identification of nontuberculous mycobacteria by MALDI‐TOF mass spectrometry
Major challenges in the identification of non‐tuberculous mycobacteria (NTM) by MALDI‐
TOF MS include protein extraction protocol and updating of the NTM database. The aim of …
TOF MS include protein extraction protocol and updating of the NTM database. The aim of …