The significant parallels between cell plasticity during embryonic development and
carcinoma progression have helped us understand the importance of the epithelial …

Stem cells have self-renewal capacities and the ability to give rise to differentiated cells
thereby sustaining tissues during homeostasis and injury. This structural hierarchy extends …

Epithelial‐mesenchymal transition (EMT) is an important process in embryonic
development, fibrosis, and cancer metastasis. During cancer progression, the activation of …

Abstract Background Treatment options for Chinese patients with locally advanced or
metastatic squamous‐cell non‐small‐cell lung cancer (sqNSCLC) after failure of first‐line …

Epithelial-mesenchymal transition (EMT) has been well recognized for its essential role in
cancer progression as well as normal tissue development. In cancer cells, activation of EMT …

The cornea is our window to the world and our vision is critically dependent on corneal
clarity and integrity. Its epithelium represents one of the most rapidly regenerating …

Purpose The corneal limbus maintains the homeostasis, immune and angiogenic privilege
of cornea. This study aimed to depict the landscape of human limbal tissues by single-cell …

Corneal stromal stem cells (CSSCs) are of particular interest in regenerative ophthalmology,
offering a new therapeutic target for corneal injuries and diseases. This review provides a …

Adult stem cell identity, plasticity, and homeostasis are precisely orchestrated by lineage-
restricted epigenetic and transcriptional regulatory networks. Here, by integrating super …

The transparent corneal epithelium in the eye is maintained through the homeostasis
regulated by limbal stem cells (LSCs), while the nontransparent epidermis relies on …