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Obesity management in adults: a review
A Elmaleh-Sachs, JL Schwartz, CT Bramante… - Jama, 2023 - jamanetwork.com
Importance Obesity affects approximately 42% of US adults and is associated with increased
rates of type 2 diabetes, hypertension, cardiovascular disease, sleep disorders …
rates of type 2 diabetes, hypertension, cardiovascular disease, sleep disorders …
Pathophysiological molecular mechanisms of obesity: a link between MAFLD and NASH with cardiovascular diseases
J Gutiérrez-Cuevas, A Santos… - International Journal of …, 2021 - mdpi.com
Obesity is now a worldwide epidemic ensuing an increase in comorbidities' prevalence,
such as insulin resistance, type 2 diabetes (T2D), metabolic dysfunction-associated fatty …
such as insulin resistance, type 2 diabetes (T2D), metabolic dysfunction-associated fatty …
Structural brain changes associated with overweight and obesity
Obesity is a global health problem with a broad set of comorbidities, such as malnutrition,
metabolic syndrome, diabetes, systemic hypertension, heart failure, and kidney failure. This …
metabolic syndrome, diabetes, systemic hypertension, heart failure, and kidney failure. This …
Therapeutic potential of semaglutide, a newer GLP-1 receptor agonist, in abating obesity, non-alcoholic steatohepatitis and neurodegenerative diseases: A narrative …
Introduction Semaglutide, a peptidic GLP-1 receptor agonist, has been clinically approved
for treatment of type 2 diabetes mellitus and is available in subcutaneous and oral dosage …
for treatment of type 2 diabetes mellitus and is available in subcutaneous and oral dosage …
Artificial intelligence and machine learning approaches using gene expression and variant data for personalized medicine
Precision medicine uses genetic, environmental and lifestyle factors to more accurately
diagnose and treat disease in specific groups of patients, and it is considered one of the …
diagnose and treat disease in specific groups of patients, and it is considered one of the …
Obesity and diabetes
C Boutari, A DeMarsilis, CS Mantzoros - Diabetes Research and Clinical …, 2023 - Elsevier
Obesity, which has currently reached pandemic dimensions, is usually accompanied by
diabetes mellitus type 2 (T2DM). These two conditions share common pathophysiological …
diabetes mellitus type 2 (T2DM). These two conditions share common pathophysiological …
Integrated network pharmacology and cellular assay for the investigation of an anti-obesity effect of 6-shogaol
W Jiao, S Mi, Y Sang, Q **, B Chitrakar, X Wang… - Food Chemistry, 2022 - Elsevier
This study explored the anti-obesity effect of 6-shogaol and the underlying mechanisms by
using Network pharmacology for the prediction and verification of molecular targets and …
using Network pharmacology for the prediction and verification of molecular targets and …
The role of AMPK signaling in brown adipose tissue activation
JI van der Vaart, MR Boon, RH Houtkooper - Cells, 2021 - mdpi.com
Obesity is becoming a pandemic, and its prevalence is still increasing. Considering that
obesity increases the risk of develo** cardiometabolic diseases, research efforts are …
obesity increases the risk of develo** cardiometabolic diseases, research efforts are …
Adiponectin and leptin in the diagnosis and therapy of NAFLD
C Boutari, CS Mantzoros - Metabolism-Clinical and …, 2020 - metabolismjournal.com
Nonalcoholic fatty liver disease (NAFLD) is the most frequent chronic liver disease and the
most prevalent cause of abnormal liver enzymes in the western world [1]. It is defined as the …
most prevalent cause of abnormal liver enzymes in the western world [1]. It is defined as the …
Dysregulated inflammation during obesity: driving disease severity in influenza virus and SARS-CoV-2 infections
Acute inflammation is a critical host defense response during viral infection. When
dysregulated, inflammation drives immunopathology and tissue damage. Excessive …
dysregulated, inflammation drives immunopathology and tissue damage. Excessive …