Progresses over the past years have extensively improved our capacity to use genome-
scale analyses—including high-density genoty** and exome and genome sequencing …

Previous studies have associated maternal diet during pregnancy with the development of
sporadic unilateral retinoblastoma (RB), but few studies have focused on the role of …

Cold atmospheric plasma (CAP) represents a novel onco-therapeutic approach that has
demonstrated its efficacy in many types of tumors. The efficacy of CAP is dose-dependent …

Retinoblastoma is a tumor of the embryonic neural retina in young children. The DNA
methyltransferase 1 (DNMT1) gene has been demonstrated to be transcriptionally activated …

Retinoblastoma (Rb) is a malignant tumor of the develo** retina that affects children
before the age of five years in association with inherited or early germline mutations of the …

Retinoblastoma is an infrequent neoplasm that arises during childhood from retinal nerve
cells and is attributed to the biallelic inactivation of the RB1 gene. In conjunction with …

The aim of the study was to investigate the frequency and types of mutations on the
retinoblastoma gene (RB1 gene) in Turkish population. RB1 gene mutation analysis was …

Purpose It is well known that individuals with hereditary retinoblastoma are at lifelong high
risk for develo** subsequent malignant neoplasms (SMN). However, the role that non …

Retinoblastoma, one of the first cancers for which a genetic basis has been explained, has
been the prototype of genetic cancers. In addition to the RB1 gene mutation, alterations in …

Background. Approximately 120 out of every 1 million children in the world develop cancer
each year. In Turkey, 2500-3000 children are diagnosed with new cancer each year. The …