Nanoscale materials are increasingly found in consumer goods, electronics, and
pharmaceuticals. While these particles interact with the body in myriad ways, their beneficial …

Dendritic cells take up antigens in peripheral tissues, process them into proteolytic peptides,
and load these peptides onto major histocompatibility complex (MHC) class I and II …

The TAT protein transduction domain (PTD) has been used to deliver a wide variety of
biologically active cargo for the treatment of multiple preclinical disease models, including …

Nanomaterials have much to offer, not only in deciphering innate immune cell biology and
tracking cells, but also in advancing personalized clinical care by providing diagnostic and …

Bone marrow–derived antigen-presenting cells (APCs) take up cell-associated antigens and
present them in the context of major histocompatibility complex (MHC) class I molecules to …

▪ Abstract The conversion of exogenous and endogenous proteins into immunogenic
peptides recognized by T lymphocytes involves a series of proteolytic and other enzymatic …

Several recent studies have shown that dendritic cells (DC) pulsed with soluble proteins can
present peptide epitopes derived from these exogenous antigens on major …

Macropinocytosis is a regulated form of endocytosis that mediates the non‐selective uptake
of solute molecules, nutrients and antigens. It is an actin‐dependent process initiated from …

Dendritic cells are cells specialized for antigen capture, migration and T cell stimulation.
Recent advances have been made in understanding their origin, their heterogeneity, the …

mRNA therapy is a novel anticancer strategy based on in vitro transcription (IVT), which has
potential for the treatment of malignant tumors. The outbreak of the COVID-19 pandemic in …