[HTML][HTML] Using biosensors to study organoids, spheroids and organs-on-a-chip: a mechanobiology perspective

MS Yousafzai, JA Hammer - Biosensors, 2023 - mdpi.com
The increasing popularity of 3D cell culture models is being driven by the demand for more
in vivo-like conditions with which to study the biochemistry and biomechanics of numerous …

Role of viscoelasticity in the appearance of low-Reynolds turbulence: considerations for modelling

I Pajic-Lijakovic, M Milivojevic… - Journal of Biological …, 2024 - Springer
Inertial effects caused by perturbations of dynamical equilibrium during the flow of soft matter
constitute a hallmark of turbulence. Such perturbations are attributable to an imbalance …

Stiffness-dependent active wetting enables optimal collective cell durotaxis

ME Pallarès, I Pi-Jaumà, IC Fortunato, V Grazu… - Nature Physics, 2023 - nature.com
The directed migration of cellular clusters enables morphogenesis, wound healing and
collective cancer invasion. Gradients of substrate stiffness direct the migration of cellular …

Cell clusters adopt a collective amoeboid mode of migration in confined nonadhesive environments

DL Pagès, E Dornier, J De Seze, E Gontran… - Science …, 2022 - science.org
Cell migration is essential to living organisms and deregulated in cancer. Single cell's
migration ranges from traction-dependent mesenchymal motility to contractility-driven …

Cell-matrix elastocapillary interactions drive pressure-based wetting of cell aggregates

MS Yousafzai, V Yadav, S Amiri, MF Staddon, Y Errami… - Physical Review X, 2022 - APS
The magnitude of mechanical stresses caused by cell surface tension may be comparable to
the bulk elasticity of their matrix on cellular length scales, yet how capillary effects influence …

Insights into adhesion and osteogenesis of bone marrow stromal cells promoted by surface nanopatterns

YT Gao, ZL Zheng, Q Sun, H Zhou, JC Lv, E Luo, JZ Xu… - Polymer, 2024 - Elsevier
The surface property of biomaterials has a profound influence on the adhesion and
biofunction of mesenchymal stem cells, which is vital for successful implantation and …

A subtle relationship between substrate stiffness and collective migration of cell clusters

HE Balcioglu, L Balasubramaniam, TV Stirbat, BL Doss… - Soft Matter, 2020 - pubs.rsc.org
The physical cues from the extracellular environment mediates cell signaling spatially and
temporally. Cells respond to physical cues from their environment in a non-monotonic …

Interplay between substrate rigidity and tissue fluidity regulates cell monolayer spreading

MF Staddon, MP Murrell, S Banerjee - Soft Matter, 2022 - pubs.rsc.org
Coordinated and cooperative motion of cells is essential for embryonic development, tissue
morphogenesis, wound healing and cancer invasion. A predictive understanding of the …

The dynamics along the biointerface between the epithelial and cancer mesenchymal cells: modeling consideration

I Pajic-Lijakovic, R Eftimie, M Milivojevic… - Seminars in Cell & …, 2023 - Elsevier
Epithelial cancer is the one of most lethal cancer type worldwide. Targeting the early stage
of disease would allow dramatic improvements in the survival of cancer patients. The early …

Vesicles with internal active filaments: self-organized propulsion controls shape, motility, and dynamical response

C Abaurrea-Velasco, T Auth… - New Journal of …, 2019 - iopscience.iop.org
Self-propulsion and navigation due to the sensing of environmental conditions—such as
durotaxis and chemotaxis—are remarkable properties of biological cells that cannot be …