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Bladder cancer
L Dyrskjøt, DE Hansel, JA Efstathiou… - Nature reviews Disease …, 2023 - nature.com
Bladder cancer is a global health issue with sex differences in incidence and prognosis.
Bladder cancer has distinct molecular subtypes with multiple pathogenic pathways …
Bladder cancer has distinct molecular subtypes with multiple pathogenic pathways …
Recurrence mechanisms of non-muscle-invasive bladder cancer—A clinical perspective
Non-muscle-invasive bladder cancer (NMIBC) is an early-stage cancer without invasion into
the detrusor muscle layer. Transurethral resection of bladder tumour (TURBT) is a diagnostic …
the detrusor muscle layer. Transurethral resection of bladder tumour (TURBT) is a diagnostic …
Construction of self-assembly based tunable absorber: lightweight, hydrophobic and self-cleaning properties
Z Zhou, Q Zhu, Y Liu, Y Zhang, Z Jia, G Wu - Nano-Micro Letters, 2023 - Springer
Although multifunctional aerogels are expected to be used in applications such as portable
electronic devices, it is still a great challenge to confer multifunctionality to aerogels while …
electronic devices, it is still a great challenge to confer multifunctionality to aerogels while …
Y chromosome loss in cancer drives growth by evasion of adaptive immunity
Loss of the Y chromosome (LOY) is observed in multiple cancer types, including 10–40% of
bladder cancers,,,,–, but its clinical and biological significance is unknown. Here, using …
bladder cancers,,,,–, but its clinical and biological significance is unknown. Here, using …
FGFR inhibition augments anti–PD-1 efficacy in murine FGFR3-mutant bladder cancer by abrogating immunosuppression
The combination of targeted therapy with immune checkpoint inhibition (ICI) is an area of
intense interest. We studied the interaction of fibroblast growth factor receptor (FGFR) …
intense interest. We studied the interaction of fibroblast growth factor receptor (FGFR) …
APOBEC3-mediated mutagenesis in cancer: causes, clinical significance and therapeutic potential
K Butler, AR Banday - Journal of Hematology & Oncology, 2023 - Springer
Apolipoprotein B mRNA-editing enzyme, catalytic polypeptides (APOBECs) are cytosine
deaminases involved in innate and adaptive immunity. However, some APOBEC family …
deaminases involved in innate and adaptive immunity. However, some APOBEC family …
The impact of FGFR3 alterations on the tumor microenvironment and the efficacy of immune checkpoint inhibitors in bladder cancer
K Komura, K Hirosuna, S Tokushige, T Tsu**o… - Molecular Cancer, 2023 - Springer
Background Currently, only limited knowledge is available regarding the phenotypic
association between fibroblast growth factor receptor 3 (FGFR3) alterations and the tumor …
association between fibroblast growth factor receptor 3 (FGFR3) alterations and the tumor …
[HTML][HTML] Elevated T-cell exhaustion and urinary tumor DNA levels are associated with Bacillus Calmette-Guérin failure in patients with non–muscle-invasive bladder …
T Strandgaard, SV Lindskrog, I Nordentoft… - European Urology, 2022 - Elsevier
Background The functional status of immune cells in the tumor microenvironment and tumor
characteristics may explain bacillus Calmette-Guérin (BCG) failure in high-risk non–muscle …
characteristics may explain bacillus Calmette-Guérin (BCG) failure in high-risk non–muscle …
Exposure to benzene and other hydrocarbons and risk of bladder cancer among male offshore petroleum workers
NK Shala, JS Stenehjem, R Babigumira, FC Liu… - British Journal of …, 2023 - nature.com
Background Occupational exposures constitute the second leading cause of urinary bladder
cancer after tobacco smoking. Increased risks have been found in the petroleum industry …
cancer after tobacco smoking. Increased risks have been found in the petroleum industry …
Circulating and urinary tumour DNA in urothelial carcinoma—Upper tract, lower tract and metastatic disease
Precision medicine has transformed the way urothelial carcinoma is managed. However,
current practices are limited by the availability of tissue samples for genomic profiling and …
current practices are limited by the availability of tissue samples for genomic profiling and …