Microneedle (MN) technologies have gained interest for biomedical applications, ranging
from drug delivery to sensing and tissue sampling in skin and internal organs. The …

Bioorthogonal chemistry is a set of methods using the chemistry of non-native functional
groups to explore and understand biology in living organisms. In this review, we summarize …

Effective reprogramming of chronic wound healing remains challenging due to the limited
drug delivery efficacy hindered by physiological barriers, as well as the inappropriate dosing …

Microneedles provide an effective strategy for transdermal drug delivery. Many endeavors
have been devoted to develo** smart microneedles that can respond to and interact with …

Acne is an inflammatory skin disease mainly caused by Propionibacterium acnes, which can
cause local inflammatory reactions and develop into chronic inflammatory diseases in …

Global increasing demand for high life quality and length facilitates the development of
tissue engineering and regenerative medicine, which apply multidisciplinary theories and …

Prodrugs have emerged as a major strategy for addressing clinical challenges by improving
drug pharmacokinetics, reducing toxicity, and enhancing treatment efficacy. The emergence …

Artificial organelles can manipulate cellular functions and introduce non-biological
processes into cells. Coacervate droplets have emerged as a close analog of …

Recent years have witnessed increasingly rapid advances in nanocarrier-based
biomedicine aimed at improving treatment paradigms for cancer. Nanogels serve as …

Non-invasive visualization of dynamic molecular events in real-time via molecular imaging
may enable the monitoring of cascade catalytic reactions in living systems, however effective …