Uric acid and hypertension: a review of evidence and future perspectives for the management of cardiovascular risk

C Borghi, D Agnoletti, AFG Cicero, E Lurbe… - Hypertension, 2022 - ahajournals.org
Uric acid is the final product of purine metabolism, and its increased serum levels have been
directly involved in the pathogenesis and natural history of hypertension. The relationship …

Hyperuricaemia and gout in cardiovascular, metabolic and kidney disease

C Borghi, E Agabiti-Rosei, RJ Johnson… - European journal of …, 2020 - Elsevier
During the last century, there has been an increasing prevalence of hyperuricaemia noted in
many populations. While uric acid is usually discussed in the context of gout …

[HTML][HTML] Uric acid in inflammation and the pathogenesis of atherosclerosis

Y Kimura, D Tsukui, H Kono - International journal of molecular sciences, 2021 - mdpi.com
Hyperuricemia is a common metabolic syndrome. Elevated uric acid levels are risk factors
for gout, hypertension, and chronic kidney diseases. Furthermore, various epidemiological …

Uric acid and cardiovascular risk

DI Feig, DH Kang, RJ Johnson - New England journal of …, 2008 - Mass Medical Soc
This review summarizes relevant studies concerning uric acid and possible links to
hypertension, renal disease, and cardiovascular disease. Whether uric acid is an …

[HTML][HTML] Fructose intake, serum uric acid, and cardiometabolic disorders: a critical review

C Caliceti, D Calabria, A Roda, AFG Cicero - Nutrients, 2017 - mdpi.com
There is a direct relationship between fructose intake and serum levels of uric acid (UA),
which is the final product of purine metabolism. Recent preclinical and clinical evidence …

Is there a pathogenetic role for uric acid in hypertension and cardiovascular and renal disease?

RJ Johnson, DH Kang, D Feig, S Kivlighn, J Kanellis… - …, 2003 - ahajournals.org
Hyperuricemia is associated with hypertension, vascular disease, renal disease, and
cardiovascular events. In this report, we review the epidemiologic evidence and potential …

Hyperuricemia and coronary heart disease: a systematic review and meta‐analysis

SY Kim, JP Guevara, KM Kim, HK Choi… - Arthritis Care & …, 2010 - Wiley Online Library
Objective The role of serum uric acid as an independent risk factor for cardiovascular
disease remains unclear, although hyperuricemia is associated with cardiovascular disease …

Hyperuricemia and the risk for coronary heart disease morbidity and mortality a systematic review and dose-response meta-analysis

M Li, X Hu, Y Fan, K Li, X Zhang, W Hou, Z Tang - Scientific reports, 2016 - nature.com
Considerable controversy exists regarding the association between hyperuricemia and
coronary heart disease (CHD). Therefore, we performed a systematic review and dose …

Uric acid is a risk factor for myocardial infarction and stroke: the Rotterdam study

MJ Bos, PJ Koudstaal, A Hofman, JCM Witteman… - Stroke, 2006 - ahajournals.org
Background and Purpose—The role of uric acid as a risk factor for myocardial infarction is
controversial, and little is known about its role as a risk factor for stroke. Recent evidence …

Potential role of uric acid in metabolic syndrome, hypertension, kidney injury, and cardiovascular diseases: is it time for reappraisal?

Z Soltani, K Rasheed, DR Kapusta, E Reisin - Current hypertension …, 2013 - Springer
Elevated serum uric acid concentration is a common laboratory finding in subjects with
metabolic syndrome/obesity, hypertension, kidney disease and cardiovascular events …