[HTML][HTML] Pharmaceutical particle technologies: An approach to improve drug solubility, dissolution and bioavailability

P Khadka, J Ro, H Kim, I Kim, JT Kim, H Kim… - Asian journal of …, 2014 - Elsevier
Pharmaceutical particle technology is employed to improve poor aqueous solubility of drug
compounds that limits in vivo bioavailability owing to their low dissolution rate in the …

Manufacturing of solid dispersions of poorly water soluble drugs by spray drying: formulation and process considerations

A Paudel, ZA Worku, J Meeus, S Guns… - International journal of …, 2013 - Elsevier
Spray drying is an efficient technology for solid dispersion manufacturing since it allows
extreme rapid solvent evaporation leading to fast transformation of an API-carrier solution to …

Formulation strategies to improve the bioavailability of poorly absorbed drugs with special emphasis on self‐emulsifying systems

S Gupta, R Kesarla, A Omri - International Scholarly Research …, 2013 - Wiley Online Library
Poorly water‐soluble drug candidates are becoming more prevalent. It has been estimated
that approximately 60–70% of the drug molecules are insufficiently soluble in aqueous …

Lipid–an emerging platform for oral delivery of drugs with poor bioavailability

S Chakraborty, D Shukla, B Mishra, S Singh - European journal of …, 2009 - Elsevier
The sole objective of pharmaceutical science is to design successful dosage forms which
fulfill the therapeutic needs of the patients effectively. Development of new drug entities is …

Spatiotemporal manipulation metal–organic frameworks as oral drug delivery systems for precision medicine

Z Wang, J Chen, R Gao, L Jiang, G Zhang… - Coordination Chemistry …, 2024 - Elsevier
Oral drug administration is the preferred method for delivering medications due to its safety,
ease of ingestion, high patient compliance, absence of pain, and adaptability to a wide …

[BOOK][B] Handbook of encapsulation and controlled release

M Mishra - 2015 - books.google.com
Written at a level comprehensible to non-experts, this handbook covers the current state of
encapsulation and controlled released technologies, presenting the fundamental processes …

[PDF][PDF] Pharmaceutical technologies for enhancing oral bioavailability of poorly soluble drugs

YSR Krishnaiah - J Bioequiv Availab, 2010 - researchgate.net
The oral bioavailability of BCS (biopharmaceutics classification system) class II drugs with
poor solubility and reasonable permeability is limited by the drug dissolution step from drug …

Enhancing curcumin oral bioavailability through nanoformulations

VS Ipar, A Dsouza, PV Devarajan - European journal of drug metabolism …, 2019 - Springer
Curcumin is a promising therapeutic agent that exhibits manifold therapeutic activities.
However, it is challenging to study curcumin as it exhibits poor aqueous solubility and low …

Self nanoemulsifying drug delivery system (SNEDDS) of rosuvastatin calcium: design, formulation, bioavailability and pharmacokinetic evaluation

K Balakumar, CV Raghavan, S Abdu - Colloids and Surfaces B …, 2013 - Elsevier
The aim of the present study is to improve solubility and bioavailability of Rosuvastatin
calcium using self nanoemulsifying drug delivery system (SNEDDS). Self emulsifying …

SNEDDS containing bioenhancers for improvement of dissolution and oral absorption of lacidipine. I: development and optimization

EB Basalious, N Shawky, SM Badr-Eldin - International journal of …, 2010 - Elsevier
The aim of this study was to develop and optimize SNEDDS formulations containing
surfactants reported to be bioenhancers for improvement of dissolution and oral absorption …