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Prescribed drugs containing nitrogen heterocycles: an overview
MM Heravi, V Zadsirjan - RSC advances, 2020 - pubs.rsc.org
Heteroatoms as well as heterocyclic scaffolds are frequently present as the common cores in
a plethora of active pharmaceuticals natural products. Statistically, more than 85% of all …
a plethora of active pharmaceuticals natural products. Statistically, more than 85% of all …
Medicinal chemistry of indole derivatives: Current to future therapeutic prospectives
A Kumari, RK Singh - Bioorganic chemistry, 2019 - Elsevier
Indole is a versatile pharmacophore, a privileged scaffold and an outstanding heterocyclic
compound with wide ranges of pharmacological activities due to different mechanisms of …
compound with wide ranges of pharmacological activities due to different mechanisms of …
Analysis of alkaloids (indole alkaloids, isoquinoline alkaloids, tropane alkaloids)
Alkaloids are a large cluster of molecules found in Mother Nature all over the world. They
are all secondary compounds and collection of miscellaneous elements and biomolecules …
are all secondary compounds and collection of miscellaneous elements and biomolecules …
Recent advances in the pharmacological diversification of quinazoline/quinazolinone hybrids
Due to the pharmacological activities of quinazoline and quinazolinone scaffolds, it has
aroused great interest in medicinal chemists for the development of new drugs or drug …
aroused great interest in medicinal chemists for the development of new drugs or drug …
Metal-mediated and metal-catalyzed reactions under mechanochemical conditions
The extraordinary impact of metal-based complexes on synthetic methods is still recognized
nowadays, and attempts are currently undertaken to further extend the use of metal-assisted …
nowadays, and attempts are currently undertaken to further extend the use of metal-assisted …
Analysis of the structural diversity, substitution patterns, and frequency of nitrogen heterocycles among US FDA approved pharmaceuticals: miniperspective
Nitrogen heterocycles are among the most significant structural components of
pharmaceuticals. Analysis of our database of US FDA approved drugs reveals that 59% of …
pharmaceuticals. Analysis of our database of US FDA approved drugs reveals that 59% of …
A study in the relationship between supportive work environment and employee retention: Role of organizational commitment and person–organization fit as …
The main aim of the study was to empirically investigate the mediating role of organizational
commitment (OC) and person–organization fit (POF) between the causal relationship of …
commitment (OC) and person–organization fit (POF) between the causal relationship of …
Indoles—A promising scaffold for drug development
TV Sravanthi, SL Manju - European Journal of Pharmaceutical Sciences, 2016 - Elsevier
Generally, heterocycles occupy a prominent place in chemistry due to their wide range of
applications in the fields of drug design, photochemistry, agrochemicals, dyes and so on …
applications in the fields of drug design, photochemistry, agrochemicals, dyes and so on …
[HTML][HTML] Heterocyclic anticancer compounds: recent advances and the paradigm shift towards the use of nanomedicine's tool box
The majority of heterocycle compounds and typically common heterocycle fragments
present in most pharmaceuticals currently marketed, alongside with their intrinsic versatility …
present in most pharmaceuticals currently marketed, alongside with their intrinsic versatility …
Recent progress in biological activities of indole and indole alkaloids
The indole scaffold is found in a wide range of bioactive heterocycles and natural products.
Moreover, the indole moiety is considered as the active principle in several alkaloids such …
Moreover, the indole moiety is considered as the active principle in several alkaloids such …