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Human genetic and immunological determinants of critical COVID-19 pneumonia
SARS-CoV-2 infection is benign in most individuals but, in around 10% of cases, it triggers
hypoxaemic COVID-19 pneumonia, which leads to critical illness in around 3% of cases …
hypoxaemic COVID-19 pneumonia, which leads to critical illness in around 3% of cases …
Persistent SARS-CoV-2 infection, EBV, HHV-6 and other factors may contribute to inflammation and autoimmunity in long COVID
A novel syndrome called long-haul COVID or long COVID is increasingly recognized in a
significant percentage of individuals within a few months after infection with SARS-CoV-2 …
significant percentage of individuals within a few months after infection with SARS-CoV-2 …
Inborn errors of OAS–RNase L in SARS-CoV-2–related multisystem inflammatory syndrome in children
Multisystem inflammatory syndrome in children (MIS-C) is a rare and severe condition that
follows benign COVID-19. We report autosomal recessive deficiencies of OAS1, OAS2, or …
follows benign COVID-19. We report autosomal recessive deficiencies of OAS1, OAS2, or …
Immunology of SARS-CoV-2 infection in children
Children and adolescents exhibit a broad range of clinical outcomes from SARS-CoV-2
infection, with the majority having minimal to mild symptoms. Additionally, some succumb to …
infection, with the majority having minimal to mild symptoms. Additionally, some succumb to …
Studying severe long COVID to understand post-infectious disorders beyond COVID-19
To the Editor—As the COVID Human Genetic Effort consortium (https://www. covidhge.
com/), we have studied genetic and immunological determinants of life-threatening COVID …
com/), we have studied genetic and immunological determinants of life-threatening COVID …
Reported cases of multisystem inflammatory syndrome in children aged 12–20 years in the USA who received a COVID-19 vaccine, December, 2020, through August …
Background Multisystem inflammatory syndrome in children (MIS-C) is a hyperinflammatory
condition associated with antecedent SARS-CoV-2 infection. In the USA, reporting of MIS-C …
condition associated with antecedent SARS-CoV-2 infection. In the USA, reporting of MIS-C …
Polyclonal expansion of TCR Vβ 21.3+ CD4+ and CD8+ T cells is a hallmark of multisystem inflammatory syndrome in children
Multisystem inflammatory syndrome in children (MIS-C) is a delayed and severe
complication of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection …
complication of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection …
[HTML][HTML] SARS-CoV-2 infections in children: Understanding diverse outcomes
SARS-CoV-2 infections mostly lead to mild or even asymptomatic infections in children, but
the reasons for this are not fully understood. More efficient local tissue responses, better …
the reasons for this are not fully understood. More efficient local tissue responses, better …
Interfering with interferons: A critical mechanism for critical COVID-19 pneumonia
HC Su, H **g, Y Zhang… - Annual review of …, 2023 - annualreviews.org
Infection with SARS-CoV-2 results in clinical outcomes ranging from silent or benign
infection in most individuals to critical pneumonia and death in a few. Genetic studies in …
infection in most individuals to critical pneumonia and death in a few. Genetic studies in …
COVID-19 and children
There has been substantial research on adult COVID-19 and how to treat it. But how do
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections afflict children …
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections afflict children …