Pathogenesis of allergic diseases and implications for therapeutic interventions

J Wang, Y Zhou, H Zhang, L Hu, J Liu, L Wang… - Signal transduction and …, 2023 - nature.com
Allergic diseases such as allergic rhinitis (AR), allergic asthma (AAS), atopic dermatitis (AD),
food allergy (FA), and eczema are systemic diseases caused by an impaired immune …

[HTML][HTML] Nociceptor neurons affect cancer immunosurveillance

M Balood, M Ahmadi, T Eichwald, A Ahmadi… - Nature, 2022 - nature.com
Solid tumours are innervated by nerve fibres that arise from the autonomic and sensory
peripheral nervous systems,,,–. Whether the neo-innervation of tumours by pain-initiating …

Targeting the peripheral neural-tumour microenvironment for cancer therapy

D Yaniv, B Mattson, S Talbot, FO Gleber-Netto… - Nature Reviews Drug …, 2024 - nature.com
As the field of cancer neuroscience expands, the strategic targeting of interactions between
neurons, cancer cells and other elements in the tumour microenvironment represents a …

Cutaneous neuroimmune interactions in peripheral neuropathic pain states

DB Lowy, PGS Makker, G Moalem-Taylor - Frontiers in Immunology, 2021 - frontiersin.org
Bidirectional interplay between the peripheral immune and nervous systems plays a crucial
role in maintaining homeostasis and responding to noxious stimuli. This crosstalk is …

Neuroimmune recognition and regulation in the respiratory system

J Chen, X Lai, Y Song, X Su - European Respiratory Review, 2024 - publications.ersnet.org
Neuroimmune recognition and regulation in the respiratory system is a complex and highly
coordinated process involving interactions between the nervous and immune systems to …

Neuroimmune interactions in the lung

R Azzoni, O Perdijk, NL Harris… - Annual review of …, 2023 - annualreviews.org
Barrier tissues are highly innervated by sensory and autonomic nerves that are positioned in
close proximity to both stromal and immune cell populations. Together with a growing …

The coding logic of interoception

RL Wang, RB Chang - Annual review of physiology, 2024 - annualreviews.org
Interoception, the ability to precisely and timely sense internal body signals, is critical for life.
The interoceptive system monitors a large variety of mechanical, chemical, hormonal, and …

Pathogenesis of children's allergic diseases: refocusing the role of the gut microbiota

T Hu, Y Dong, C Yang, M Zhao, Q He - Frontiers in physiology, 2021 - frontiersin.org
Allergic diseases comprise a genetically heterogeneous cluster of immunologically
mediated diseases, including asthma, food allergy (FA), allergic rhinitis (AR) and eczema …

Sensory neuronal control of skin barrier immunity

X Feng, H Zhan, CL Sokol - Trends in Immunology, 2024 - cell.com
Peripheral sensory neurons recognize diverse noxious stimuli, including microbial products
and allergens traditionally thought to be targets of the mammalian immune system …

Further understanding of neuro-immune interactions in allergy: implications in pathophysiology and role in disease progression

GN Konstantinou, GN Konstantinou… - Journal of Asthma …, 2022 - Taylor & Francis
The complicated interaction between the central and the autonomic (sympathetic,
parasympathetic, and enteric) nervous systems on the one hand and the immune system …