The African turquoise killifish has recently gained significant traction as a new research
organism in the aging field. Our understanding of aging has strongly benefited from …

The emergence of collagen I in vertebrates resulted in a dramatic increase in the stiffness of
the extracellular environment, supporting long-range force propagation and the …

Angiogenesis, the process of new blood vessels formation from existing vasculature, plays a
vital role in development, wound healing, and various pathophysiological conditions. In …

In biomimetic design, researchers recreate existing biological structures to form functional
devices. For biohybrid robotic swimmers assembled with tissue engineering, this is …

Twin-core fiber (TCF)-based sensor was proposed for non-invasive vital sign monitoring,
including respiration and heartbeat. The TCF was homemade and the corresponding sensor …

The mechanisms of the evolution and development of the heart in metazoans are
highlighted, starting with the evolutionary origin of the contractile cell, supposedly the …

Retinoic acid (RA) is a vitamin A metabolite that acts as a morphogen and teratogen. Excess
or defective RA signaling causes developmental defects including in the heart. The heart …

Mitral valve prolapse is a common cardiac condition, with an estimated prevalence between
1% and 3%. Most patients have a benign course, but ever since its initial description mitral …

The adult mammalian heart cannot regenerate after myocardial injury because most
cardiomyocytes lack the ability to proliferate. In contrast, cardiomyocytes of vertebrates such …

Primitive underpinnings of the alternative pathway (AP), namely, a C3‐like protein, likely
arose more than a billion years ago. The development of an AP amplification loop, while …