Evaluation of the TCR repertoire as a predictive and prognostic biomarker in cancer: diversity or clonality?
A Aran, L Garrigós, G Curigliano, J Cortés, M Martí - Cancers, 2022 - mdpi.com
Simple Summary The TCR is the T cell antigen receptor, and it is responsible of the T cell
activation, through the HLA-antigen complex recognition. Studying the TCR repertoire in …
activation, through the HLA-antigen complex recognition. Studying the TCR repertoire in …
Autoimmune and Neoplastic Outcomes After the mRNA Vaccination: The Role of T Regulatory Cell Responses
AM Kyriakopoulos, G Nigh, PA McCullough… - International Journal of …, 2024 - ijvtpr.com
A plethora of autoimmune disease incidences occured after COVID-19 mRNA injections
were rolled out. Aggressive cancer cases have occurred in the bodies of recipients at sites …
were rolled out. Aggressive cancer cases have occurred in the bodies of recipients at sites …
Nanovaccine displaying immunodominant T cell epitopes of fibroblast activation protein is effective against desmoplastic tumors
Cancer-associated fibroblasts (CAFs), which are dominant cell types in the tumor
microenvironment (TME), support tumor growth by secreting cytokines and forming an …
microenvironment (TME), support tumor growth by secreting cytokines and forming an …
SARS-CoV-2 infection triggers auto-immune response in ARDS
Acute respiratory distress syndrome (ARDS) is a severe pulmonary disease, which is one of
the major complications in COVID-19 patients. Dysregulation of the immune system and …
the major complications in COVID-19 patients. Dysregulation of the immune system and …
Association of elevated autoantibody to high expression of GNAS in hepatocellular carcinoma
Purpose This study was based on hepatocellular carcinoma (HCC) patients of early-stage to
explore the diagnostic capability and possible production causes of anti-GNAS …
explore the diagnostic capability and possible production causes of anti-GNAS …
Bioinformatics analysis of the pathogenic link between Epstein-Barr virus infection, systemic lupus erythematosus and diffuse large B cell lymphoma
QY Zhu - Scientific Reports, 2023 - nature.com
Epstein-Barr virus (EBV) is a risk factor for diffuse large B-cell lymphoma (DLBCL) and
systemic lupus erythematosus (SLE). While prior research has suggested a potential …
systemic lupus erythematosus (SLE). While prior research has suggested a potential …
Potential medicinal value of N6‐methyladenosine in autoimmune diseases and tumours
Q Geng, X Cao, D Fan, Q Wang, X Wang… - British Journal of …, 2023 - Wiley Online Library
Autoimmune diseases (ADs) are closely related to malignant tumours. On the one hand,
ADs can increase the incidence of tumours; on the other hand, malignant tumours can cause …
ADs can increase the incidence of tumours; on the other hand, malignant tumours can cause …
Extracellular vesicle autoantibodies
Y Hua, P Jiang, C Dai, M Li - Journal of Autoimmunity, 2024 - Elsevier
Autoantibodies are immunoglobulin proteins produced by autoreactive B cells responding to
self-antigens. Extracellular vesicles (EVs) are membranous structures released by almost all …
self-antigens. Extracellular vesicles (EVs) are membranous structures released by almost all …
State-Of-The-Art Advancements on Cancer Vaccines and Biomarkers
S Strum, MH Andersen, IM Svane, LL Siu… - American Society of …, 2024 - ascopubs.org
The origins of cancer vaccines date back to the 1800s. Since then, there have been
significant efforts to generate vaccines against solid and hematologic malignancies using a …
significant efforts to generate vaccines against solid and hematologic malignancies using a …
[HTML][HTML] Immune Checkpoint Inhibitor-Associated Cutaneous Adverse Events: Mechanisms of Occurrence
AM Eshaq, TW Flanagan, AA Ba Abbad… - International Journal of …, 2024 - mdpi.com
Immunotherapy, particularly that based on blocking checkpoint proteins in many tumors,
including melanoma, Merkel cell carcinoma, non-small cell lung cancer (NSCLC), triple …
including melanoma, Merkel cell carcinoma, non-small cell lung cancer (NSCLC), triple …