Metabolic influences of gut microbiota dysbiosis on inflammatory bowel disease

S Sultan, M El-Mowafy, A Elgaml, TAE Ahmed… - Frontiers in …, 2021 - frontiersin.org
Inflammatory bowel diseases (IBD) are chronic medical disorders characterized by recurrent
gastrointestinal inflammation. While the etiology of IBD is still unknown, the pathogenesis of …

[HTML][HTML] Antioxidant therapy for treatment of inflammatory bowel disease: does it work?

FA Moura, KQ de Andrade, JCF Dos Santos… - Redox biology, 2015 - Elsevier
Oxidative stress (OS) is considered as one of the etiologic factors involved in several signals
and symptoms of inflammatory bowel diseases (IBD) that include diarrhea, toxic megacolon …

A new three-dimensional zinc (II) metal–organic framework as a fluorescence sensor for sensing the biomarker 3-nitrotyrosine

J Geng, Y Li, H Lin, Q Liu, J Lu, X Wang - Dalton Transactions, 2022 - pubs.rsc.org
3-Nitrotyrosine (3-NT), an oxidative stress biomarker, is closely associated with various
diseases. Thus, rapid and sensitive detection of 3-NT is of great significance for preventing …

Dysfunction of the intestinal microbiome in inflammatory bowel disease and treatment

XC Morgan, TL Tickle, H Sokol, D Gevers, KL Devaney… - Genome biology, 2012 - Springer
Background The inflammatory bowel diseases (IBD) Crohn's disease and ulcerative colitis
result from alterations in intestinal microbes and the immune system. However, the precise …

Redox signaling in the gastrointestinal tract

S Pérez, R Taléns-Visconti, S Rius-Pérez… - Free Radical Biology …, 2017 - Elsevier
Redox signaling regulates physiological self-renewal, proliferation, migration and
differentiation in gastrointestinal epithelium by modulating Wnt/β-catenin and Notch …

Inflammatory bowel disease: cause and immunobiology

DC Baumgart, SR Carding - The Lancet, 2007 - thelancet.com
Crohn's disease and ulcerative colitis are idiopathic inflammatory bowel disorders. In this
paper, we discuss how environmental factors (eg, geography, cigarette smoking, sanitation …

[HTML][HTML] NADPH oxidases and ROS signaling in the gastrointestinal tract

G Aviello, UG Knaus - Mucosal immunology, 2018 - Elsevier
Reactive oxygen species (ROS), initially categorized as toxic by-products of aerobic
metabolism, have often been called a double-edged sword. ROS are considered …

Intestinal barrier dysfunction as a therapeutic target for cardiovascular disease

CV Lewis, WR Taylor - American Journal of Physiology …, 2020 - journals.physiology.org
The gut microbiome and intestinal dysfunction have emerged as potential contributors to the
development of cardiovascular disease (CVD). Alterations in gut microbiome are well …

Dietary protein oxidation: A silent threat to human health?

M Estévez, C Luna - Critical reviews in food science and nutrition, 2017 - Taylor & Francis
Protein oxidation has become a topic of great scientific interest in the field of food science
and nutrition. Food proteins are known to be preferential targets of radical species, and …