The effects of sepsis on endothelium and clinical implications
EV Dolmatova, K Wang, R Mandavilli… - Cardiovascular …, 2021 - academic.oup.com
Sepsis accounts for nearly 700 000 deaths in Europe annually and is caused by an
overwhelming host response to infection resulting in organ failure. The endothelium is an …
overwhelming host response to infection resulting in organ failure. The endothelium is an …
Cancer-associated fibroblasts: mechanisms of tumor progression and novel therapeutic targets
Simple Summary The tumor microenvironment plays an important role in determining the
biological behavior of several of the more aggressive malignancies. Among the various cell …
biological behavior of several of the more aggressive malignancies. Among the various cell …
N6-methyladenosine induced miR-143-3p promotes the brain metastasis of lung cancer via regulation of VASH1
H Wang, Q Deng, Z Lv, Y Ling, X Hou, Z Chen… - Molecular cancer, 2019 - Springer
Background Brain metastasis (BM) is one of the principal causes of mortality for lung cancer
patients. While the molecular events that govern BM of lung cancer remain frustrating …
patients. While the molecular events that govern BM of lung cancer remain frustrating …
Aberrant expression of microRNAs in bladder cancer
H Yoshino, N Seki, T Itesako, T Chiyomaru… - Nature Reviews …, 2013 - nature.com
MicroRNAs (miRNAs), a class of small noncoding RNAs, regulate protein-coding gene
expression by repressing translation or cleaving RNA transcripts in a sequence-specific …
expression by repressing translation or cleaving RNA transcripts in a sequence-specific …
miR-143 and miR-145 inhibit gastric cancer cell migration and metastasis by suppressing MYO6
C Lei, F Du, L Sun, T Li, T Li, Y Min, A Nie, X Wang… - Cell death & …, 2017 - nature.com
Metastasis is a major clinical obstacle responsible for the high mortality and poor prognosis
of gastric cancer (GC). MicroRNAs (miRNAs) are critical mediators of metastasis that act by …
of gastric cancer (GC). MicroRNAs (miRNAs) are critical mediators of metastasis that act by …
Long non‐coding RNA urothelial cancer‐associated 1 promotes bladder cancer cell migration and invasion by way of the hsa‐miR‐145–ZEB 1/2–FSCN 1 pathway
M Xue, H Pang, X Li, H Li, J Pan, W Chen - Cancer science, 2016 - Wiley Online Library
Numerous studies suggest that several long non‐coding RNA s (lnc RNA s) play critical
roles in bladder cancer development and progression. Long non‐coding RNA urothelial …
roles in bladder cancer development and progression. Long non‐coding RNA urothelial …
[HTML][HTML] uPA/uPAR and SERPINE1 in head and neck cancer: role in tumor resistance, metastasis, prognosis and therapy
MA Pavón, I Arroyo-Solera, MV Céspedes… - Oncotarget, 2016 - ncbi.nlm.nih.gov
There is strong evidence supporting the role of the plasminogen activator system in head
and neck squamous cell carcinoma (HNSCC), particularly of its uPA (urokinase …
and neck squamous cell carcinoma (HNSCC), particularly of its uPA (urokinase …
Micro RNA‐145: a potent tumour suppressor that regulates multiple cellular pathways
SY Cui, R Wang, LB Chen - Journal of cellular and molecular …, 2014 - Wiley Online Library
Micro RNA s are endogenous, small (18–25 nucleotides) non‐coding RNA s, which regulate
genes expression by directly binding to the 3′‐untranslated regions of the target …
genes expression by directly binding to the 3′‐untranslated regions of the target …
Analysis of the combined action of miR-143 and miR-145 on oncogenic pathways in colorectal cancer cells reveals a coordinate program of gene repression
A Pagliuca, C Valvo, ED Fabrizi, S Di Martino, M Biffoni… - Oncogene, 2013 - nature.com
MicroRNAs (miRNAs) from the gene cluster miR-143–145 are diminished in cells of
colorectal tumor origin when compared with normal colon epithelia. Until now, no report has …
colorectal tumor origin when compared with normal colon epithelia. Until now, no report has …
microRNA expression profile in a large series of bladder tumors: identification of a 3‐miRNA signature associated with aggressiveness of muscle‐invasive bladder …
G Pignot, G Cizeron‐Clairac, S Vacher… - … journal of cancer, 2013 - Wiley Online Library
The aim of this study was to evaluate the expression levels of microRNAs (miRNAs) in
bladder tumors in order to identify miRNAs involved in bladder carcinogenesis with potential …
bladder tumors in order to identify miRNAs involved in bladder carcinogenesis with potential …