Cardiac optical map** has proven to be a powerful technology for studying cardiovascular
function and disease. The development and scientific impact of this methodology are well …

Optical map** has become an increasingly important tool to study cardiac
electrophysiology in the past 20 years. Multiple methods are used to process and analyze …

Rationale: Human induced pluripotent stem cell–derived cardiomyocytes (iPSC-CMs) offer a
powerful in vitro tool to investigate disease mechanisms and to perform patient-specific drug …

Cardiac side effects are one of the major causes of drug candidate failures in preclinical
drug development or in clinical trials and are responsible for the retraction of several already …

We report simulated and experimental image quality for contact imaging, a method for
imaging objects close to the sensor surface without intervening optics. This technique …

Optical map** of cardiac excitation using voltage-and calcium-sensitive dyes has allowed
a unique view into excitation wave dynamics, and facilitated scientific discovery in the …

Optical map** is a powerful imaging technique widely adopted to measure membrane
potential changes and intracellular Ca2+ variations in excitable tissues using voltage …

Combined optogenetic stimulation and optical imaging permit scalable, contact-free high-
throughput probing of cellular electrophysiology and optimization of stem-cell derived …

BACKGROUND: Simultaneous optical map** of multiple electrophysiologically relevant
parameters in living myocardium is desirable for integrative exploration of mechanisms …

Significance All-optical cardiac electrophysiology enables the visualization and control of
key parameters relevant to the detection of cardiac arrhythmias. Map** such responses in …