The mechanisms of lysophosphatidylcholine in the development of diseases
Lysophosphatidylcholine (LPC) is the main component of oxidatively damaged low-density
lipoprotein (oxLDL). LPC originates from the cleavage of phosphatidylcholine by …
lipoprotein (oxLDL). LPC originates from the cleavage of phosphatidylcholine by …
Schistosome egg migration: mechanisms, pathogenesis and host immune responses
Many parasitic worms possess complex and intriguing life cycles, and schistosomes are no
exception. To exit the human body and progress to their successive snail host, Schistosoma …
exception. To exit the human body and progress to their successive snail host, Schistosoma …
Gut microbiota-mediated lysophosphatidylcholine generation promotes colitis in intestinal epithelium-specific Fut2 deficiency
X Tang, W Wang, G Hong, C Duan, S Zhu… - Journal of Biomedical …, 2021 - Springer
Background and aims Previous study disclosed Fucosyltransferase 2 (Fut2) gene as a IBD
risk locus. This study aimed to explore the mechanism of Fut2 in IBD susceptibility and to …
risk locus. This study aimed to explore the mechanism of Fut2 in IBD susceptibility and to …
[HTML][HTML] Helminth extracellular vesicles: Interactions with the host immune system
C Drurey, RM Maizels - Molecular Immunology, 2021 - Elsevier
As long-lived parasites, helminths depend upon immunomodulation of their hosts for
survival. The release of excretory-secretory (ES) products, including proteins, lipids and …
survival. The release of excretory-secretory (ES) products, including proteins, lipids and …
Tumor hijacks macrophages and microbiota through extracellular vesicles
J Jiang, J Mei, Y Ma, S Jiang, J Zhang, S Yi… - …, 2022 - Wiley Online Library
The tumor microenvironment (TME) is a biological system with sophisticated constituents. In
addition to tumor cells, tumor‐associated macrophages (TAMs) and microbiota are also …
addition to tumor cells, tumor‐associated macrophages (TAMs) and microbiota are also …
Tumor associated macrophage and microbe: The potential targets of tumor vaccine delivery
J Jiang, J Mei, S Yi, C Feng, Y Ma, Y Liu, Y Liu… - Advanced drug delivery …, 2022 - Elsevier
The occurrence and development of tumors depend on the tumor microenvironment (TME),
which is made of various immune cells, activated fibroblasts, basement membrane …
which is made of various immune cells, activated fibroblasts, basement membrane …
Schistosome immunomodulators
Schistosomes are long lived, intravascular parasitic platyhelminths that infect> 200 million
people globally. The molecular mechanisms used by these blood flukes to dampen host …
people globally. The molecular mechanisms used by these blood flukes to dampen host …
Metabolic programming of macrophages: implications in the pathogenesis of granulomatous disease
JL Wilson, HK Mayr, T Weichhart - Frontiers in immunology, 2019 - frontiersin.org
Metabolic reprogramming is rapidly gaining appreciation in the etiology of immune cell
dysfunction in a variety of diseases. Tuberculosis, schistosomiasis, and sarcoidosis …
dysfunction in a variety of diseases. Tuberculosis, schistosomiasis, and sarcoidosis …
Lysophosphatidylcholine induces NLRP3 inflammasome-mediated foam cell formation and pyroptosis in human monocytes and endothelial cells
Foam cells are specialized lipid-loaded macrophages derived from monocytes and are a
key pathological feature of atherosclerotic lesions. Lysophosphatidylcholine (LPC) is a …
key pathological feature of atherosclerotic lesions. Lysophosphatidylcholine (LPC) is a …
Quercetin serves as the major component of ** the balance of STAT1/PPARγ and dictating the alternative …
H Zhou, C Yang, J Li, Y He, Y Huang, R Qin… - Journal of …, 2023 - Elsevier
Abstract Ethnopharmacological relevance The traditional Chinese herbal formula, **ang-
lian Pill (XLP), is commonly prescribed for ulcerative colitis (UC) patients to relieve their …
lian Pill (XLP), is commonly prescribed for ulcerative colitis (UC) patients to relieve their …