[HTML][HTML] Two novel compounds, ergosterol and ergosta-5, 8-dien-3-ol, from Termitomyces heimii Natarajan demonstrate promising anti-hepatocarcinoma activity
R Ray, S Saha, S Paul - Journal of Traditional Chinese Medical Sciences, 2022 - Elsevier
Background Mushroom-derived components have immense potential to become a safe
alternative in identifying lead anti-cancer molecules. Termitomyces heimii Natarajan (T …
alternative in identifying lead anti-cancer molecules. Termitomyces heimii Natarajan (T …
Identification of new inhibitors against human Great wall kinase using in silico approaches
Microtubule associated serine/threonine kinase (MASTL) is an important Ser/Thr kinase
belonging to the family of AGC kinases. It is the human orthologue of Greatwall kinase (Gwl) …
belonging to the family of AGC kinases. It is the human orthologue of Greatwall kinase (Gwl) …
Synthesis and in vitro study of nitro-and methoxy-2-phenylbenzofurans as human monoamine oxidase inhibitors
A new series of 2-phenylbenzofuran derivatives were designed and synthesized to
determine relevant structural features for the MAO inhibitory activity and selectivity. Methoxy …
determine relevant structural features for the MAO inhibitory activity and selectivity. Methoxy …
New molecular scaffolds for the design of Alzheimer's acetylcholinesterase inhibitors identified using ligand-and receptor-based virtual screening
The identification of important chemical features of acetylcholinesterase (AChE) inhibitors
will be helpful to discover the potent candidate to inhibit the AChE activity. The best …
will be helpful to discover the potent candidate to inhibit the AChE activity. The best …
[PDF][PDF] In Vitro screening and in silico docking analysis identifies two novel compound lecanoric acid and atranorin from Parmotrema tinctorum, exhibiting potent anti …
S Saha, R Ray, S Paul - Biointerface Res Appl Chem, 2023 - biointerfaceresearch.com
Lichens are a good repository of bio-active compounds with different pharmacological
properties; therefore, in our article, we aim to screen the antiproliferative potential of three …
properties; therefore, in our article, we aim to screen the antiproliferative potential of three …
Interaction between shrimp and white spot syndrome virus through PmRab7-VP28 complex: an insight using simulation and docking studies
White spot disease is a devastating disease of shrimp Penaeus monodon in which the
shrimp receptor protein PmRab7 interacts with viral envelop protein VP28 to form PmRab7 …
shrimp receptor protein PmRab7 interacts with viral envelop protein VP28 to form PmRab7 …
Receptor based virtual screening of potential novel inhibitors of tigar [TP53 (tumour protein 53)-induced glycolysis and apoptosis regulator
Abstract TP53 (tumor protein 53)-induced glycolysis and apoptosis regulator (TIGAR)
belongs to the phosphatases family of proteins that modulates the level of reactive oxygen …
belongs to the phosphatases family of proteins that modulates the level of reactive oxygen …
Bio/chemoinformatics in India: an outlook
With the advent of significant establishment and development of Internet facilities and
computational infrastructure, an overview on bio/chemoinformatics is presented along with …
computational infrastructure, an overview on bio/chemoinformatics is presented along with …
[PDF][PDF] In silico docking studies of alkyl esters derivative of gallic acid on Bcl-xL anti-apoptotic protein of breast cancer
Gallic acid has been reported to have various biological activities including an anticancer
effect. Numerous studies have indicated that alkyl esters derivative of gallic acid are more …
effect. Numerous studies have indicated that alkyl esters derivative of gallic acid are more …
[PDF][PDF] Synthesis and cytotoxic activities of hexyl esters derivatives of gallic acid against MCF-7 cell line
Gallic acid is found in many plants, fruits, and foods where the anti-cancer activity is found.
However, gallic acid has a problem on the high polarity and low bio availability. So, it takes …
However, gallic acid has a problem on the high polarity and low bio availability. So, it takes …