[NiFe]-hydrogenases catalyze the reversible conversion of hydrogen gas into protons and
electrons and are vital metabolic components of many species of bacteria and archaea. At …

Numerous recent developments in the biochemistry, molecular biology, and physiology of
formate and H2 metabolism and of the [NiFe]-hydrogenase (Hyd) cofactor biosynthetic …

Hydrogenases and ureases play vital metabolic functions in all three domains of life.
However, nickel ions are cytotoxic because they can inactivate enzymes that require less …

Cellular metal homeostasis is a critical process for all organisms, requiring tight regulation.
In the major pathogen Helicobacter pylori, the acquisition of nickel is an essential virulence …

Hydrogenases are biotechnologically relevant metalloenzymes that catalyze the reversible
conversion of molecular hydrogen into protons and electrons. The O2-tolerant [NiFe] …

Escherichia coli growth and H 2 production were followed in the presence of heavy metal
ions and their mixtures during glycerol or glucose fermentation at pH 5.5–7.5. Ni 2+(50 μM) …

SlyD is a widely-occurring prokaryotic FKBP-family prolyl isomerase with an additional
chaperone domain. Often, such as in Escherichia coli, a third domain is found at its C …

[NiFe]-hydrogenases have attracted attention as potential therapeutic targets or components
of a hydrogen-based economy.[NiFe]-hydrogenase production is a complicated process that …

Nickel participates in important biochemical processes in many prokaryotes. Nickel-
requiring microorganisms thus have developed elaborate systems to maintain the …

Nickel is essential for the survival of many pathogenic bacteria. E. coli and H. pylori require
nickel for [NiFe]-hydrogenases. H. pylori also requires nickel for urease. At high …