Per‐and polyfluoroalkyl substance toxicity and human health review: Current state of knowledge and strategies for informing future research

SE Fenton, A Ducatman, A Boobis… - Environmental …, 2021 - academic.oup.com
Reports of environmental and human health impacts of per‐and polyfluoroalkyl substances
(PFAS) have greatly increased in the peer‐reviewed literature. The goals of the present …

Endocrine disrupting chemicals: exposure, effects on human health, mechanism of action, models for testing and strategies for prevention

B Yilmaz, H Terekeci, S Sandal… - Reviews in endocrine and …, 2020 - Springer
Abstract Endocrine Disrupting Chemicals (EDCs) are a global problem for environmental
and human health. They are defined as “an exogenous chemical, or mixture of chemicals …

A review of the pathways of human exposure to poly-and perfluoroalkyl substances (PFASs) and present understanding of health effects

EM Sunderland, XC Hu, C Dassuncao… - Journal of exposure …, 2019 - nature.com
Here, we review present understanding of sources and trends in human exposure to poly-
and perfluoroalkyl substances (PFASs) and epidemiologic evidence for impacts on cancer …

Risk to human health related to the presence of perfluoroalkyl substances in food

EFSA Panel on Contaminants in the Food Chain … - EFSA …, 2020 - Wiley Online Library
Abstract The European Commission asked EFSA for a scientific evaluation on the risks to
human health related to the presence of perfluoroalkyl substances (PFAS s) in food. Based …

Perfluoroalkyl/polyfluoroalkyl substances: links to cardiovascular disease risk

JJ Schlezinger, N Gokce - Circulation research, 2024 - ahajournals.org
Conservative estimates by the World Health Organization suggest that at least a quarter of
global cardiovascular diseases are attributable to environmental exposures. Associations …

[HTML][HTML] Exposure to environmental toxicants is associated with gut microbiome dysbiosis, insulin resistance and obesity

P Sen, Y Fan, JJ Schlezinger, SD Ehrlich… - Environment …, 2024 - Elsevier
Environmental toxicants (ETs) are associated with adverse health outcomes. Here we
hypothesized that exposures to ETs are linked with obesity and insulin resistance partly …

[HTML][HTML] Exposure to perfluoroalkyl chemicals and cardiovascular disease: experimental and epidemiological evidence

A Meneguzzi, C Fava, M Castelli… - Frontiers in endocrinology, 2021 - frontiersin.org
Polyfluoro-and perfluoro–alkyl substances (PFAS) are organic chemicals extensively used
worldwide for industry and consumer products. Due to their chemical stability, PFAS …

All-cause, cardiovascular disease and cancer mortality in the population of a large Italian area contaminated by perfluoroalkyl and polyfluoroalkyl substances (1980 …

A Biggeri, G Stoppa, L Facciolo, G Fin, S Mancini… - Environmental …, 2024 - Springer
Background Per-and polyfluoroalkyl substances (PFAS) are associated with many adverse
health conditions. Among the main effects is carcinogenicity in humans, which deserves to …

PFAS environmental pollution and antioxidant responses: an overview of the impact on human field

M Bonato, F Corrà, M Bellio, L Guidolin… - International journal of …, 2020 - mdpi.com
Due to their unique properties, perfluorinated substances (PFAS) are widely used in multiple
industrial and commercial applications, but they are toxic for animals, humans included. This …

Serum levels of perfluoroalkyl substances (PFAS) in adolescents and young adults exposed to contaminated drinking water in the Veneto region, Italy: a cross …

G Pitter, F Da Re, C Canova, G Barbieri… - Environmental …, 2020 - ehp.niehs.nih.gov
Background: In spring 2013, groundwater of a vast area of the Veneto Region (northeastern
Italy) was found to be contaminated by perfluoroalkyl substances (PFAS) from a PFAS …