Streptozotocin as a tool for induction of rat models of diabetes: A practical guide

A Ghasemi, S Jeddi - EXCLI journal, 2023 - pmc.ncbi.nlm.nih.gov
Streptozotocin (STZ) is the most used diabetogenic chemical for creating rat models of type
1 and type 2 diabetes. Despite~ 60 years of using STZ in animal diabetes research, some …

Guidelines for the use of flow cytometry and cell sorting in immunological studies

A Cossarizza, HD Chang, A Radbruch… - European journal of …, 2021 - Wiley Online Library
The third edition of Flow Cytometry Guidelines provides the key aspects to consider when
performing flow cytometry experiments and includes comprehensive sections describing …

In situ forming and reactive oxygen species-scavenging gelatin hydrogels for enhancing wound healing efficacy

P Le Thi, Y Lee, DL Tran, TTH Thi, JI Kang, KM Park… - Acta biomaterialia, 2020 - Elsevier
The overexpression of reactive oxygen species (ROS) contributes to the pathogenesis of
numerous diseases such as atherosclerosis, myocardial infarction, cancer, and chronic …

Stimuli-responsive graphdiyne-silver nanozymes for catalytic ion therapy of dental caries through targeted biofilms removal and remineralization

J Liao, L Zhang, B Sun, D Wang, Z Zhang, W Ma… - Nano Today, 2024 - Elsevier
Clinical mechanical decontamination and irrigants are not consistently effective in
preventing intractable biofilm-induced dental caries, especially when biofilms have caused …

Clinical hematological and biochemical parameters in Swiss, BALB/c, C57BL/6 and B6D2F1 Mus musculus

G Silva‐Santana, JC Bax… - Animal models and …, 2020 - Wiley Online Library
Background Animal models are widely used in scientific research in order to obtain
information from a whole organism under a specific set of experimental conditions. Various …

Small-molecule inhibition of the acyl-lysine reader ENL as a strategy against acute myeloid leukemia

Y Liu, Q Li, F Alikarami, DR Barrett, L Mahdavi… - Cancer …, 2022 - aacrjournals.org
The chromatin reader eleven–nineteen leukemia (ENL) has been identified as a critical
dependency in acute myeloid leukemia (AML), but its therapeutic potential remains unclear …

A polymer-based systemic hemostatic agent

Y Gao, A Sarode, N Kokoroskos, A Ukidve, Z Zhao… - Science …, 2020 - science.org
Uncontrolled noncompressible hemorrhage is a major cause of mortality following traumatic
injuries in civilian and military populations. An injectable hemostat for point-of-care treatment …

Large extracellular vesicle (EV) and neutrophil extracellular trap (NET) interaction captured in vivo during systemic inflammation

W Ortmann, A Such, I Cichon, M Baj-Krzyworzeka… - Scientific Reports, 2024 - nature.com
Extracellular vesicles (EVs) and neutrophil extracellular traps (NETs) are pivotal bioactive
structures involved in various processes including inflammation. Herein we report the …

Influence of magnetic nanoparticle biotransformation on contrasting efficiency and iron metabolism

AV Yaremenko, IV Zelepukin, IN Ivanov… - Journal of …, 2022 - Springer
Magnetic nanoparticles are widely used in biomedicine for MRI imaging and anemia
treatment. The aging of these nanomaterials in vivo may lead to gradual diminishing of their …

Antioxidant, anti‐inflammatory, hypoglycemic, and anti‐hyperglycemic activity of chickpea protein hydrolysates evaluated in BALB‐c mice

A Navarro‐Leyva, G López‐Angulo… - Journal of Food …, 2023 - Wiley Online Library
Chickpea (ICC3761) protein hydrolysates have shown high in vitro antioxidant activity
(AoxA) and antidiabetic potential. The aim of this study was to evaluate the in vivo activities …