Oxidative stress and diabetic retinopathy: development and treatment

GD Calderon, OH Juarez, GE Hernandez, SM Punzo… - Eye, 2017 - nature.com
Diabetic retinopathy (DR) is the most common microvascular complication in diabetic
patients and one of the main causes of acquired blindness in the world. From the 90s until …

Neurovascular unit in diabetic retinopathy: pathophysiological roles and potential therapeutical targets

S Nian, ACY Lo, Y Mi, K Ren, D Yang - Eye and Vision, 2021 - Springer
Diabetic retinopathy (DR), one of the common complications of diabetes, is the leading
cause of visual loss in working-age individuals in many industrialized countries. It has been …

Adipose tissue-derived stem cells: immunomodulatory effects and therapeutic potential

S Al-Ghadban, BA Bunnell - Physiology, 2020 - journals.physiology.org
Adipose-derived stem cells (ASCs) can self-renew and differentiate along multiple cell
lineages. ASCs are also potently anti-inflammatory due to their inherent ability to regulate …

Stem cell therapy for retinal degeneration: the evidence to date

A Sharma, BG Jaganathan - Biologics: Targets and Therapy, 2021 - Taylor & Francis
There is a rise in the number of people who have vision loss due to retinal diseases, and
conventional therapies for treating retinal degeneration fail to repair and regenerate the …

Stromal vascular fraction: A regenerative reality? Part 1: Current concepts and review of the literature

A Nguyen, J Guo, DA Banyard, D Fadavi… - Journal of Plastic …, 2016 - Elsevier
Summary Stromal Vascular Fraction (SVF) is a heterogeneous collection of cells contained
within adipose tissue that is traditionally isolated using enzymes such as collagenase. With …

Ocular complications of diabetes and therapeutic approaches

VJ Vieira-Potter, D Karamichos… - BioMed research …, 2016 - Wiley Online Library
Diabetes mellitus (DM) is a metabolic disease defined by elevated blood glucose (BG). DM
is a global epidemic and the prevalence is anticipated to continue to increase. The ocular …

Adipose extracellular matrix/stromal vascular fraction gel: a novel adipose tissue–derived injectable for stem cell therapy

Y Yao, Z Dong, Y Liao, P Zhang, J Ma… - Plastic and …, 2017 - journals.lww.com
Background: Adipose-derived stem cells and other stromal vascular fraction cells were used
more often for stem cell therapy, even though limitations such as poor cell retention rate …

Stromal vascular fraction: A regenerative reality? Part 2: Mechanisms of regenerative action

J Guo, A Nguyen, DA Banyard, D Fadavi… - Journal of Plastic …, 2016 - Elsevier
Adipose tissue is a rich source of cells with emerging promise for tissue engineering and
regenerative medicine. The stromal vascular fraction (SVF), in particular, is an eclectic …

The adipose stromal vascular fraction as a complex cellular source for tissue engineering applications

VM Ramakrishnan, NL Boyd - Tissue Engineering Part B: Reviews, 2018 - liebertpub.com
A major challenge in tissue engineering is the generation of sufficient volumes of viable
tissue for organ transplant. The development of a stable, mature vasculature is required to …

Mesenchymal stem cell-based therapy for retinal degenerative diseases: experimental models and clinical trials

V Holan, K Palacka, B Hermankova - Cells, 2021 - mdpi.com
Retinal degenerative diseases, such as age-related macular degeneration, retinitis
pigmentosa, diabetic retinopathy or glaucoma, represent the main causes of a decreased …